WB (Western Blot)
(Western blot of Nogo-A and -B in A) human, B) mouse, and C) rat brain tissue lysate using antibody at 1:2000.)
Rabbit RTN4 / Nogo Polyclonal Antibody | anti-RTN4 antibody
Rabbit Polyclonal to Human RTN4 / Nogo
Gene Names
RTN4; ASY; NSP; NOGO; NOGOC; RTN-X; NOGO-A; NSP-CL; Nogo-B; Nogo-C; RTN4-A; RTN4-C; RTN4-B1; RTN4-B2; NI220/250; Nbla00271; Nbla10545
Reactivity
Gibbon, Human, Monkey, Mouse, Pig, RatPredicted Reactivity: Bovine (at least 90% immunogen sequence identity)
Applications
Western Blot, Immunohistochemistry
Purity
Unpurified serum
Synonyms
RTN4 / Nogo, Antibody; Rabbit Polyclonal to Human RTN4 / Nogo; Anti-RTN4 / Nogo Antibody (aa14-30) IHC-plus; RTN4; Human NogoA; My043 protein; Neurite outgrowth inhibitor; NOGOC; NSP-CL; Nogo protein; KIAA0886; Reticulon 5; Reticulon-4; Reticulon-5; Reticulon 4; RTN4-B1; RTN-X; RTN4-A; RTN4-B2; RTN4-C; Nbla00271; Neurite growth inhibitor 220; NI220/250; Nogo; Human RTN4; anti-RTN4 antibody
Host
Rabbit
Reactivity
Gibbon, Human, Monkey, Mouse, Pig, Rat
Predicted Reactivity: Bovine (at least 90% immunogen sequence identity)
Predicted Reactivity: Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
A synthetic sequence corresponding to amino acids 14-30 (DSPPRPQPAFKYQFVRE) of human Nogo-B was used as the immunogen.
Purity/Purification
Unpurified serum
Form/Format
PBS containing 0.05% BSA and 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
1192
Applicable Applications for anti-RTN4 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
A synthetic sequence corresponding to amino acids 14-30 (DSPPRPQPAFKYQFVRE) of human Nogo-B was used as the immunogen, GenBank no. AAG40878.1|AF320999_1.
Immunogen
RTN4 / Nogo antibody was raised against a synthetic sequence corresponding to amino acids 14-30 (DSPPRPQPAFKYQFVRE) of human Nogo-B was used as the immunogen, GenBank no. AAG40878.1|AF320999_1. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Pig (100%); Bovine (94%); Mouse, Rat, Bat, Dog (88%); Opossum (82%).
Antigen Modification
aa14-30
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
WB (Western Blot)
(Western blot of Nogo-A and -B in A) human, B) mouse, and C) rat brain tissue lysate using antibody at 1:2000.)
WB (Western Blot)
(Western blot of Nogo-A and -B in A) human, B) mouse, and C) rat brain tissue lysate using antibody at 1:2000.)
IHC (Immunohistochemistry)
(Anti-RTN4 / Nogo antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
IHC (Immunohistochemistry)
(Anti-RTN4 / Nogo antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Related Product Information for anti-RTN4 antibody
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.
Product Categories/Family for anti-RTN4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
108,450 Da
NCBI Official Full Name
reticulon-4 isoform A
NCBI Official Synonym Full Names
reticulon 4
NCBI Official Symbol
RTN4
NCBI Official Synonym Symbols
ASY; NSP; NOGO; NOGOC; RTN-X; NOGO-A; NSP-CL; Nogo-B; Nogo-C; RTN4-A; RTN4-C; RTN4-B1; RTN4-B2; NI220/250; Nbla00271; Nbla10545
NCBI Protein Information
reticulon-4; foocen; Human NogoA; reticulon 5; My043 protein; neurite outgrowth inhibitor; neurite growth inhibitor 220; neuroendocrine-specific protein C homolog
UniProt Protein Name
Reticulon-4
UniProt Gene Name
RTN4
UniProt Synonym Gene Names
KIAA0886; NOGO; Nogo protein; NSP
UniProt Entry Name
RTN4_HUMAN
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Product Notes
The RTN4 rtn4 (Catalog #AAA51415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human RTN4 / Nogo reacts with Gibbon, Human, Monkey, Mouse, Pig, Rat Predicted Reactivity: Bovine (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's RTN4 / Nogo can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the RTN4 rtn4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RTN4 / Nogo, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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