IHC (Immunohiostchemistry)
(Immunochemical staining of human RUVBL1 in human testis with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human RUVBL1 Polyclonal Antibody | anti-RUVBL1 antibody
Anti-RUVBL1 Antibody, Rabbit Polyclonal
Gene Names
RUVBL1; RVB1; TIH1; ECP54; TIP49; INO80H; NMP238; PONTIN; TIP49A; Pontin52
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
RUVBL1, Antibody; Anti-RUVBL1 Antibody, Rabbit Polyclonal; RUVBL1 Antibody, Rabbit PAb, Antigen Affinity Purified; RuvB-like AAA ATPase 1; Anti-ECP-54 Antibody; Anti-ECP54 Antibody; Anti-INO80H Antibody; Anti-NMP 238 Antibody; Anti-NMP238 Antibody; Anti-PONTIN Antibody; Anti-Pontin52 Antibody; Anti-RVB1 Antibody; Anti-TIH1 Antibody; Anti-TIP49 Antibody; Anti-TIP49A Antibody; anti-RUVBL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human RUVBL1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-RUVBL1 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant Human RUVBL1 Protein ( Q9Y265-1; Met1-Lys456). RUVBL1 specific IgG was purified by Human RUVBL1 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
IHC (Immunohiostchemistry)
(Immunochemical staining of human RUVBL1 in human testis with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human RUVBL1 in human testis with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human RUVBL1 in human carcinoma of sigmoid with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human RUVBL1 in human carcinoma of sigmoid with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-RUVBL1 antibody
RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. RUVBL1 is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. It also is essential for cell proliferation. RUVBL1 may be able to bind plasminogen at cell surface and enhance plasminogen activation.
References
Baue. A. e. al. (1998. Pontin52. a. interactio. partne. o. beta-catenin. bind. t. th. TAT. bo. bindin. protein. Pro. Nat. Aca. Sci. 95(25):14787-92.Ewing. e. al. (2007. Large-scal. mappin. o. huma. protein-protei. interaction. b. mas. spectrometry. Mo. Sys. Biol. 3(1):89.Pur. T. e. al. (2007. Dodecameri. structur. an. ATPas. activit. o. th. huma. TIP48/TIP4. complex. . Mo. Biol. 366(1):179-92.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,127 Da
NCBI Official Full Name
Homo sapiens RuvB-like AAA ATPase 1 (RUVBL1), mRNA
NCBI Official Synonym Full Names
RuvB-like AAA ATPase 1
NCBI Official Symbol
RUVBL1
NCBI Official Synonym Symbols
RVB1; TIH1; ECP54; TIP49; INO80H; NMP238; PONTIN; TIP49A; Pontin52
NCBI Protein Information
ruvB-like 1; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; NMP 238; RuvB (E coli homolog)-like 1; TAP54-alpha; TATA binding protein interacting p
UniProt Protein Name
RuvB-like 1
UniProt Gene Name
RUVBL1
UniProt Synonym Gene Names
INO80H; NMP238; TIP49; TIP49A; 49 kDa TBP-interacting protein; ECP-54; NMP 238; TAP54-alpha
UniProt Entry Name
RUVB1_HUMAN
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Product Notes
The RUVBL1 ruvbl1 (Catalog #AAA259432) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RUVBL1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RUVBL1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the RUVBL1 ruvbl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RUVBL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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