Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody detects endogenous levels of S26A7 at Human/Mouse
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-S26A7 antibody
WB (Western Blot)
Immunogen
Synthesized peptide derived from human S26A7 AA range: 595-645
Organism
Human, Mouse
Cellular Localization
Recycling endosome membrane ; Multi-pass membrane protein . Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion.
Tissue specificity
Expressed in tonsillar high endothelial venule endothelial cells (HEVEC), placenta and in testis, expressed in a subgroup of basal cells in the epididymal ducts.
Function
Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger. Plays a major role in gastric acid secretion.,miscellaneous:Is active at both alkaline and acidic pH. Activity is inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS - an inhibitor of several anionic channels and transporters).,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 STAS domain.,subcellular location:Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion.,tissue specificity:Expressed in tonsilar high endothelial venule enothelial cells (HEVEC), placenta and in testis, expressed in a subgroup of basal cells in the epididymal ducts
Preparation and Storage
Store at -15 degree C to -25 degree C (Do not lower than -25 degree C)
Related Product Information for anti-S26A7 antibody
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]
Product Categories/Family for anti-S26A7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72kD (Observed)
NCBI Official Full Name
anion exchange transporter isoform a
NCBI Official Synonym Full Names
solute carrier family 26 (anion exchanger), member 7
NCBI Official Symbol
SLC26A7
NCBI Official Synonym Symbols
SUT2
NCBI Protein Information
anion exchange transporter; sulfate anion transporter; solute carrier family 26, member 7
UniProt Protein Name
Anion exchange transporter
UniProt Gene Name
SLC26A7
UniProt Synonym Gene Names
SUT2
UniProt Entry Name
S26A7_HUMAN
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Product Notes
The S26A7 slc26a7 (Catalog #AAA269130) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S26A7 rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's S26A7 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the S26A7 slc26a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S26A7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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