IHC (Immunohistochemisry)
Chicken SGK3 Polyclonal Antibody | anti-SGK3 antibody
SGK3 Antibody
Gene Names
SGK3; CISK; SGK2; SGKL
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
Synonyms
SGK3, Antibody; SGK3 Antibody; CISK; Cytokine independent survival kinase; DKFZp781N0293; Serine/threonine protein kinase Sgk3; Serum/glucocorticoid regulated kinase family member 3; Serum/glucocorticoid-regulated kinase 3; SGK 3; Sgk3; SGKL antibody; anti-SGK3 antibody
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.6 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
496
Applicable Applications for anti-SGK3 antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy)
Immunogen
Synthetic peptide taken within amino acid region 440-490 on human Sgk3 protein.
Immunoglobulin
IgY
Expression
Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle. Expression is higher in ER-positive breast tumors than ER-negative breast tumors.
Molecular Function
ATP-binding, Nucleotide binding; Kinase, Serine/threonine-protein kinase, Transferase
Structure
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
Contains 1 PX (phox homology) domain.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
Contains 1 PX (phox homology) domain.
Subcellular Location
Cytoplasmic vesicle; Early endosome; Recycling endosome
Preparation and Storage
-20 degree C for long term storage
IHC (Immunohistochemisry)
IHC (Immunohistochemisry)
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-SGK3 antibody
Affinity Purified Serine/Threonine-protein Kinase Sgk3 Antibody
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.
Product Categories/Family for anti-SGK3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,306 Da
NCBI Official Full Name
Serine/threonine-protein kinase Sgk3
NCBI Official Synonym Full Names
serum/glucocorticoid regulated kinase family member 3
NCBI Official Symbol
SGK3
NCBI Official Synonym Symbols
CISK; SGK2; SGKL
NCBI Protein Information
serine/threonine-protein kinase Sgk3
UniProt Protein Name
Serine/threonine-protein kinase Sgk3
UniProt Gene Name
SGK3
UniProt Synonym Gene Names
CISK; SGKL
UniProt Entry Name
SGK3_HUMAN
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Product Notes
The SGK3 sgk3 (Catalog #AAA76048) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The SGK3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SGK3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy). Researchers should empirically determine the suitability of the SGK3 sgk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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