IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SIGLEC8 Polyclonal Antibody at dilution 1:25)
Rabbit anti-Human SIGLEC8 Polyclonal Antibody | anti-SIGLEC8 antibody
SIGLEC8 Polyclonal Antibody
Gene Names
SIGLEC8; SAF2; SIGLEC-8; SIGLEC8L
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
SIGLEC8, Antibody; SIGLEC8 Polyclonal Antibody; SAF2; SIGLEC-8; SIGLEC8L; anti-SIGLEC8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
1.5mg/ml (varies by lot)
Sequence Length
499
Applicable Applications for anti-SIGLEC8 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human SIGLEC8
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47418
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SIGLEC8 Polyclonal Antibody at dilution 1:25)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SIGLEC8 Polyclonal Antibody at dilution 1:25)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using SIGLEC8 Polyclonal Antibody at dilution 1:25)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using SIGLEC8 Polyclonal Antibody at dilution 1:25)
Related Product Information for anti-SIGLEC8 antibody
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,434 Da
NCBI Official Full Name
sialic acid-binding Ig-like lectin 8
NCBI Official Synonym Full Names
sialic acid binding Ig like lectin 8
NCBI Official Symbol
SIGLEC8
NCBI Official Synonym Symbols
SAF2; SIGLEC-8; SIGLEC8L
NCBI Protein Information
sialic acid-binding Ig-like lectin 8
UniProt Protein Name
Sialic acid-binding Ig-like lectin 8
UniProt Gene Name
SIGLEC8
UniProt Synonym Gene Names
SAF2; Siglec-8; SAF-2
UniProt Entry Name
SIGL8_HUMAN
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Product Notes
The SIGLEC8 siglec8 (Catalog #AAA173255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIGLEC8 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIGLEC8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SIGLEC8 siglec8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIGLEC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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