Rabbit SIK2 Polyclonal Antibody | anti-SIK2 antibody

SIK2 Antibody

Cat. Num. AAA39925

• Gene Names: SIK2; QIK; SIK-2; SNF1LK2; LOH11CR1I
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: SIK2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: SIK2, Antibody; SIK2 Antibody; SIK2; QIK; SNF1LK2; LOH11CR1I; KIAA0781; Qin-induced kinase; SIK-2; salt-inducible kinase 2; anti-SIK2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: SIK2 antibody is predicted to not cross-react with other SIK protein family members.
• Purity/Purification: SIK2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 926

• Applicable Applications for anti-SIK2 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: SIK2 antibody was raised against a 16 amino acid synthetic peptide near the center of human SIK2.
• Buffer: SIK2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: SIK2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of SIK2 in SW480 cells with SIK2 antibody at 5 μg/ml.)

ICC (Immunocytochemistry)

(Immunocytochemistry of SIK2 in SW480 cells with SIK2 antibody at 2.5 μg/ml.)

WB (Western Blot)

(Western blot analysis of SIK2 in SW480 cell lysate with SIK2 antibody at 1 μg/mL.)

Related Product Information for anti-SIK2 antibody

SIK2 Antibody: Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1 alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.

NCBI and Uniprot Product Information

• NCBI GI #: 38569460
• NCBI GeneID: 23235
• NCBI Accession #: EAW67148
• NCBI GenBank Nucleotide #: NM_015191.2
• UniProt Accession #: Q9H0K1; O94878; Q17RV0; Q6AZE2; Q76N03; Q8NCV7; Q96CZ8; A8K5B8; B0YJ94
• Molecular Weight: 103,915 Da
• NCBI Official Full Name: serine/threonine-protein kinase SIK2
• NCBI Official Synonym Full Names: salt-inducible kinase 2
• NCBI Official Symbol: SIK2
• NCBI Official Synonym Symbols: QIK; SIK-2; SNF1LK2; LOH11CR1I
• NCBI Protein Information: serine/threonine-protein kinase SIK2; SNF1-like kinase 2; qin-induced kinase; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SNF1-like kinase 2
• UniProt Protein Name: Serine/threonine-protein kinase SIK2
• UniProt Gene Name: SIK2
• UniProt Synonym Gene Names: SIK-2
• UniProt Entry Name: SIK2_HUMAN