IF (Immunofluorescence)
(Immunofluorescence of Slug in human kidney tissue with Slug antibody at 20 ug/mL.)
Rabbit anti-Human, Mouse Slug Polyclonal Antibody | anti-Slug antibody
Slug Antibody
Gene Names
SNAI2; SLUG; WS2D; SLUGH1; SNAIL2
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Slug, Antibody; Slug Antibody; Neural crest transcription factor slug, Snail homolog 2; anti-Slug antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
268
Applicable Applications for anti-Slug antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the center of human Slug.
Target Name
Slug
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of Slug in human kidney tissue with Slug antibody at 20 ug/mL.)
IF (Immunofluorescence)
(Immunofluorescence of Slug in human kidney tissue with Slug antibody at 20 ug/mL.)
WB (Western Blot)
(Western blot analysis of Slug in 293 cell lysate with Slug antibody at in (A) 0.5, (B) 1 and (C) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of Slug in 293 cell lysate with Slug antibody at in (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Related Product Information for anti-Slug antibody
Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family. Slug antibody has no cross-reactivity to Snail protein.
Product Categories/Family for anti-Slug antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,986 Da
NCBI Official Full Name
zinc finger protein SNAI2
NCBI Official Synonym Full Names
snail family zinc finger 2
NCBI Official Symbol
SNAI2
NCBI Official Synonym Symbols
SLUG; WS2D; SLUGH1; SNAIL2
NCBI Protein Information
zinc finger protein SNAI2
UniProt Protein Name
Zinc finger protein SNAI2
UniProt Gene Name
SNAI2
UniProt Synonym Gene Names
SLUG; SLUGH
UniProt Entry Name
SNAI2_HUMAN
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Product Notes
The Slug snai2 (Catalog #AAA306982) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Slug Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Slug can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Slug snai2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Slug, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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