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product-image-AAA254641_IHC13.png IHC (Immunohiostchemistry) (Immunochemical staining of human SMAD7 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

Rabbit smad7 Polyclonal Antibody | anti-SMAD7 antibody

Anti-smad7 Antibody, Rabbit Polyclonal

Gene Names
SMAD7; CRCS3; MADH7; MADH8
Reactivity
Human
Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
smad7, Antibody; Anti-smad7 Antibody, Rabbit Polyclonal; SMAD7 Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-CRCS3 Antibody; Anti-MADH7 Antibody; Anti-MADH8 Antibody; anti-SMAD7 antibody
Ordering
Host
Rabbit
Reactivity
Human
Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human smad7
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SMAD7 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human SMAD7
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human SMAD7, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohiostchemistry)

(Immunochemical staining of human SMAD7 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

product-image-AAA254641_IHC13.png IHC (Immunohiostchemistry) (Immunochemical staining of human SMAD7 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining of human SMAD7 in human liver with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)

product-image-AAA254641_IHC15.png IHC (Immunohistochemistry) (Immunochemical staining of human SMAD7 in human liver with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-SMAD7 antibody
SMAD7-epigenetic modified gene related to atherosclerosis. SMAD7 methylation as a novel marker in atherosclerosis and further elucidate the role of Hcy in atherogenesis. Atherosclerosis is a complicated process comprising inflammation, accumulation of collagen matrix and aberrant DNA methylation. SMAD7 is known to play an important role in fibrosis and inflammation. SMAD7 may be a novel predicted marker and therapeutic target for atherosclerosis. SMAD7 attenuated the TGF-beta signaling pathway in ovarian granulosa cells (GCs) by regulating TGFBR1 transcriptional activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,426 Da
NCBI Official Full Name
Smad7
NCBI Official Synonym Full Names
SMAD family member 7
NCBI Official Symbol
SMAD7
NCBI Official Synonym Symbols
CRCS3; MADH7; MADH8
NCBI Protein Information
mothers against decapentaplegic homolog 7; hSMAD7; MAD homolog 8; mothers against DPP homolog 8; SMAD, mothers against DPP homolog 7; Mothers against decapentaplegic, drosophila, homolog of, 7; MAD (mothers against decapentaplegic, Drosophila) homolog 7
UniProt Protein Name
Mothers against decapentaplegic homolog 7
UniProt Gene Name
SMAD7
UniProt Synonym Gene Names
MADH7; MADH8; MAD homolog 7; Mothers against DPP homolog 7; MAD homolog 8; Mothers against DPP homolog 8; SMAD 7; Smad7; hSMAD7
UniProt Entry Name
SMAD7_HUMAN

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Product Notes

The SMAD7 smad7 (Catalog #AAA254641) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-smad7 Antibody, Rabbit Polyclonal reacts with Human Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's smad7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SMAD7 smad7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "smad7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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