WB (Western Blot)
(Western blot analysis of extracts from MCF-7 cells, using SMC4 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit SMC4 Polyclonal Antibody | anti-SMC4 antibody
SMC4 Antibody
Gene Names
SMC4; CAPC; CAP-C; SMC-4; SMC4L1
Reactivity
Human, RatPredicted: Pig, Horse, Sheep, Rabbit, Dog
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SMC4, Antibody; SMC4 Antibody; CAP C; CAPC; Chromosome associated polypeptide C; Chromosome-associated polypeptide C; hCAP C; hCAP-C; SMC 4; SMC protein 4; SMC-4; SMC4; SMC4_HUMAN; SMC4L1; Structural maintenance of chromosomes 4; Structural maintenance of chromosomes 4 like 1; Structural maintenance of chromosomes protein 4; XCAP C homolog; XCAP-C homolog; anti-SMC4 antibody
Host
Rabbit
Reactivity
Human, Rat
Predicted: Pig, Horse, Sheep, Rabbit, Dog
Predicted: Pig, Horse, Sheep, Rabbit, Dog
Clonality
Polyclonal
Isotype
IgG
Specificity
SMC4 Antibody detects endogenous levels of SMC4.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1288
Applicable Applications for anti-SMC4 antibody
WB (Western Blot)
Immunogen
A synthesized peptide derived from human SMC4.
Tissue Specificity
Widely expressed. Higher expression in testis, colon, thymus.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Nucleus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from MCF-7 cells, using SMC4 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from MCF-7 cells, using SMC4 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Rat brain, using SMC4 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Rat brain, using SMC4 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-SMC4 antibody
Description: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subunit Structure: Forms a heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG.
Similarity: The hinge domain, which separates the large intramolecular coiled coil regions, allows the heterodimerization with SMC2, forming a V-shaped heterodimer. Belongs to the SMC family. SMC4 subfamily.
Subunit Structure: Forms a heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG.
Similarity: The hinge domain, which separates the large intramolecular coiled coil regions, allows the heterodimerization with SMC2, forming a V-shaped heterodimer. Belongs to the SMC family. SMC4 subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 150 kDa
Predicted: 148 kDa
Predicted: 148 kDa
NCBI Official Full Name
structural maintenance of chromosomes protein 4 isoform 1
NCBI Official Synonym Full Names
structural maintenance of chromosomes 4
NCBI Official Symbol
SMC4
NCBI Official Synonym Symbols
CAPC; CAP-C; SMC-4; SMC4L1
NCBI Protein Information
structural maintenance of chromosomes protein 4
UniProt Protein Name
Structural maintenance of chromosomes protein 4
UniProt Gene Name
SMC4
UniProt Synonym Gene Names
CAPC; SMC4L1; SMC protein 4; SMC-4; hCAP-C
UniProt Entry Name
SMC4_HUMAN
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Product Notes
The SMC4 smc4 (Catalog #AAA328616) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMC4 Antibody reacts with Human, Rat Predicted: Pig, Horse, Sheep, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's SMC4 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the SMC4 smc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMC4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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