Rabbit anti-Human SMC4 Polyclonal Antibody | anti-SMC4 antibody
SMC4 antibody (pAb)
WB (Western Blot)
(SMC4 antibody (pAb) tested by Western blot Nuclear extract of HeLa cells (20 ?g) probed with SMC4 antibody (1:1,000).)
WB (Western Blot)
(SMC4 antibody (pAb) tested by Immunoprecipitation. 10 ul of SMC4 antibody was used to immunoprecipitate SMC4 from 500 ug of HeLa nuclear cell extract (lane 2). 10 ul of rabbit IgG was used as a negative control (lane 1). The immunoprecipitated protein was detected by Western blotting using the SMC4 antibody at a dilution of 1:1,000.)
Background: The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into condensed mitotic chromosomes. SMC4 forms a heterodimer with SMC2 and contains a myosin-like ATPase domain that serves as a molecular motor to help organize chromatin. During mitosis, most of the condensin complex is associated with the chromatin.
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Product Notes
The SMC4 smc4 (Catalog #AAA59983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMC4 antibody (pAb) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMC4 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the SMC4 smc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMC4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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