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product-image-AAA229588_IP13.jpg IP (Immunoprecipitation) (Immunoprecipitating SMPD3 in mouse brain whole cell lysateLane 1: Rabbit control IgG (1ug)instead of AAA229588 in mouse brain whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)Lane 2: AAA229588 (6ug)+ mouse brain whole cell lysate (500ug)Lane 3: Mouse brain whole cell lysate (10ug))

Rabbit anti-Human SMPD3 Polyclonal Antibody | anti-SMPD3 antibody

SMPD3 Antibody

Gene Names
SMPD3; NSMASE2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
>95%,Protein G purified
Synonyms
SMPD3, Antibody; SMPD3 Antibody; Sphingomyelin phosphodiesterase 3; Neutral sphingomyelinase 2; nSMase-2; nSMase2; Neutral sphingomyelinase II; SMPD3; anti-SMPD3 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
655
Applicable Applications for anti-SMPD3 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Recombinant human Sphingomyelin phosphodiesterase 3 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-67692 / sc-67693 / sc-67305
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

IP (Immunoprecipitation)

(Immunoprecipitating SMPD3 in mouse brain whole cell lysateLane 1: Rabbit control IgG (1ug)instead of AAA229588 in mouse brain whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)Lane 2: AAA229588 (6ug)+ mouse brain whole cell lysate (500ug)Lane 3: Mouse brain whole cell lysate (10ug))

product-image-AAA229588_IP13.jpg IP (Immunoprecipitation) (Immunoprecipitating SMPD3 in mouse brain whole cell lysateLane 1: Rabbit control IgG (1ug)instead of AAA229588 in mouse brain whole cell lysate. For western blotting,a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)Lane 2: AAA229588 (6ug)+ mouse brain whole cell lysate (500ug)Lane 3: Mouse brain whole cell lysate (10ug))

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using AAA229588 at dilution 1:100)

product-image-AAA229588_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using AAA229588 at dilution 1:100)
Related Product Information for anti-SMPD3 antibody
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,170 Da
NCBI Official Full Name
sphingomyelin phosphodiesterase 3
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 3
NCBI Official Symbol
SMPD3
NCBI Official Synonym Symbols
NSMASE2
NCBI Protein Information
sphingomyelin phosphodiesterase 3
UniProt Protein Name
Sphingomyelin phosphodiesterase 3
UniProt Gene Name
SMPD3
UniProt Synonym Gene Names
nSMase-2; nSMase2
UniProt Entry Name
NSMA2_HUMAN

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Product Notes

The SMPD3 smpd3 (Catalog #AAA229588) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMPD3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMPD3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SMPD3 smpd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMPD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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