IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using AAA229777 at dilution of 1:100)
Rabbit anti-Human SNX6 Polyclonal Antibody | anti-SNX6 antibody
SNX6 Antibody
Gene Names
SNX6; TFAF2; MSTP010
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity Purified
Synonyms
SNX6, Antibody; SNX6 Antibody; Sorting nexin-6; SNX6; TRAF4-associated factor 2; Cleaved into the following chain:; N-terminally processed; anti-SNX6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
290
Applicable Applications for anti-SNX6 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant human Sorting nexin-6 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5260 / sc-8679 / sc-50373
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using AAA229777 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using AAA229777 at dilution of 1:100)
WB (Western Blot)
(Western blotAll lanes: SNX6 antibody at 4ug/ml+ Hela whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 47,34 kDaObserved band size: 47 kDa)
WB (Western Blot)
(Western blotAll lanes: SNX6 antibody at 4ug/ml+ Hela whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 47,34 kDaObserved band size: 47 kDa)
Related Product Information for anti-SNX6 antibody
Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R (PubMed:17148574). May function as link between transport vesicles and dynactin (Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network (PubMed:20354142). Involved in E-cadherin sorting and degradation; inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B (By similarity). May contribute to transcription regulation (Probable).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,570 Da
NCBI Official Full Name
sorting nexin-6 isoform a
NCBI Official Synonym Full Names
sorting nexin 6
NCBI Official Symbol
SNX6
NCBI Official Synonym Symbols
TFAF2; MSTP010
NCBI Protein Information
sorting nexin-6
UniProt Protein Name
Sorting nexin-6
UniProt Gene Name
SNX6
UniProt Entry Name
SNX6_HUMAN
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Product Notes
The SNX6 snx6 (Catalog #AAA229777) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNX6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SNX6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SNX6 snx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNX6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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