IHC (Immunohiostchemistry)
(Anti-SOCS1 antibody, AAA45103, IHC(P)IHC(P): Rat Spleen Tissue)
Rabbit SOCS1 Polyclonal Antibody | anti-SOCS1 antibody
Anti-SOCS1 antibody
Gene Names
SOCS1; JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; SOCS-1
Reactivity
Human, Rat Predicted: Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
SOCS1, Antibody; Anti-SOCS1 antibody; Suppressor of cytokine signaling 1(SOCS-1); suppressor of cytokine signaling 1; CISH 1 antibody; CISH1 antibody; Cytokine Inducible SH2 Protein 1 antibody; JAB antibody; JAK Binding Protein antibody; JAK-binding protein antibody; Janus kinase binding protein antibody; SOCS 1 antibody; SOCS-1 antibody; Socs1 antibody; SOCS1_HUMAN antibody; SSI 1 antibody; SSI-1 antibody; SSI1 antibody; STAT Induced STAT Inhibitor 1 antibody; STAT-induced STAT inhibitor 1 antibody; Suppressor of cytokine signaling 1 antibody; Supressor of cytokine Signalling 1 antibody; TEC Interacting Protein 3 antibody; Tec-interacting protein 3 antibody; TIP 3 antibody; TIP-3 antibody; TIP3 antibody; anti-SOCS1 antibody
Host
Rabbit
Reactivity
Human, Rat
Predicted: Mouse
Predicted: Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
211
Applicable Applications for anti-SOCS1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1, identical to the related mouse and rat sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and store frozen at -20°C for longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-SOCS1 antibody, AAA45103, IHC(P)IHC(P): Rat Spleen Tissue)
IHC (Immunohiostchemistry)
(Anti-SOCS1 antibody, AAA45103, IHC(P)IHC(P): Rat Spleen Tissue)
WB (Western Blot)
(Anti-SOCS1 antibody, AAA45103, Western blottingLane 1: HT1080 Cell LysateLane 2: COLO320 Cell Lysate)
WB (Western Blot)
(Anti-SOCS1 antibody, AAA45103, Western blottingLane 1: HT1080 Cell LysateLane 2: COLO320 Cell Lysate)
Related Product Information for anti-SOCS1 antibody
Description: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 1(SOCS1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.
Background: Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Suppressor of cytokine signaling 1
NCBI Official Synonym Full Names
suppressor of cytokine signaling 1
NCBI Official Symbol
SOCS1
NCBI Official Synonym Symbols
JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; SOCS-1
NCBI Protein Information
suppressor of cytokine signaling 1; TIP-3; JAK binding protein; JAK-binding protein; Tec-interacting protein 3; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; cytokine-inducible SH2 protein 1
UniProt Protein Name
Suppressor of cytokine signaling 1
UniProt Gene Name
SOCS1
UniProt Synonym Gene Names
SSI1; TIP3; SOCS-1; JAB; SSI-1; TIP-3
UniProt Entry Name
SOCS1_HUMAN
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Product Notes
The SOCS1 socs1 (Catalog #AAA45103) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOCS1 antibody reacts with Human, Rat Predicted: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SOCS1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SOCS1 socs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOCS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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