Application Data
(ICC image of SOX2 antibody stained human F9 cells (A) and NCCIT cells (B). The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.)
anti-Human, Mouse SOX2 Polyclonal Antibody | anti-SOX2 antibody
SOX2 Antibody
Gene Names
SOX2; ANOP3; MCOPS3
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot
Purity
Affinity Purified
Synonyms
SOX2, Antibody; SOX2 Antibody; anti-SOX2 antibody
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of SOX2.
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
317
Applicable Applications for anti-SOX2 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Cellular Localization
Nucleus Cell Nucleus
Positive Control
F9, MCF-7, NCCIT
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Application Data
(ICC image of SOX2 antibody stained human F9 cells (A) and NCCIT cells (B). The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.)
Application Data
(ICC image of SOX2 antibody stained human F9 cells (A) and NCCIT cells (B). The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.)
Application Data
(Western blot analysis on F9 (A)and MCF-7(B) cell lysates using anti-SOX2 rabbit polyclonal antibody.)
Application Data
(Western blot analysis on F9 (A)and MCF-7(B) cell lysates using anti-SOX2 rabbit polyclonal antibody.)
Related Product Information for anti-SOX2 antibody
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells.
Product Categories/Family for anti-SOX2 antibody
References
1. "Mutations in SOX2 cause anophthalmia."Fantes J., Ragge N.K., Lynch S.-A., McGill N.I., Collin J.R.O., Howard-Peebles P.N., Hayward C., Vivian A.J., Williamson K., van Heyningen V., FitzPatrick D.R.Nat. Genet. 33:461-463(2003). 2. "Induction of pluripotent stem cells from adult human fibroblasts by defined factors."Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S.Cell 131:861-872(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33kDa
NCBI Official Full Name
transcription factor SOX-2
NCBI Official Synonym Full Names
SRY-box 2
NCBI Official Symbol
SOX2
NCBI Official Synonym Symbols
ANOP3; MCOPS3
NCBI Protein Information
transcription factor SOX-2
UniProt Protein Name
Transcription factor SOX-2
UniProt Gene Name
SOX2
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Product Notes
The SOX2 sox2 (Catalog #AAA111015) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SOX2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SOX2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SOX2 sox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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