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WB (Western Blot)
(Anti-SOX2 antibody, AAA45727, All Western blottingAll lanes: Anti-SOX2(AAA45727) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: Mouse Brain Tissue Lysate at 40ugPredicted bind size: 34KDObserved bind size: 34KD)
Rabbit SOX2 Polyclonal Antibody | anti-SOX2 antibody
Anti-SOX2 antibody
Gene Names
SOX2; ANOP3; MCOPS3
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
SOX2, Antibody; Anti-SOX2 antibody; Transcription factor SOX-2; SRY(sex determining region Y)-box 2; ANOP3 antibody; cb236 antibody; Delta EF2a antibody; lcc antibody; MCOPS3 antibody; MGC148683 antibody; MGC2413 antibody; RGD1565646 antibody; Sex determining region Y box 2 antibody; SOX 2 antibody; Sox2 antibody; SRY(sex determining region Y) box 2 antibody; SRY box containing gene 2 antibody; SRY related HMG box 2 antibody; SRY related HMG box gene 2 antibody; SRY-box 2 antibody; Transcription factor SOX 2 antibody; Transcription factor SOX-2 antibody; ysb antibody; anti-SOX2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
317
Applicable Applications for anti-SOX2 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SOX2 (171-183aa YSMMQDQLGYPQH), different from the related mouse and rat sequence by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-SOX2 antibody, AAA45727, All Western blottingAll lanes: Anti-SOX2(AAA45727) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: Mouse Brain Tissue Lysate at 40ugPredicted bind size: 34KDObserved bind size: 34KD)
WB (Western Blot)
(Anti-SOX2 antibody, AAA45727, All Western blottingAll lanes: Anti-SOX2(AAA45727) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: Mouse Brain Tissue Lysate at 40ugPredicted bind size: 34KDObserved bind size: 34KD)
IHC (Immunohistochemisry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemisry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Mouse Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Mouse Brain Tissue)
IHC (Immunohistochemistry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Rat Lung Tissue)
IHC (Immunohistochemistry)
(Anti-SOX2 antibody, AAA45727, IHC(P)IHC(P): Rat Lung Tissue)
Related Product Information for anti-SOX2 antibody
Description: Rabbit IgG polyclonal antibody for Transcription factor SOX-2(SOX2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: SRY(sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. Sox2 is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. This gene is mapped to 3q26.33. It is found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. SOX2 is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, SOX2 has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.
Background: SRY(sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. Sox2 is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. This gene is mapped to 3q26.33. It is found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. SOX2 is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, SOX2 has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,310 Da
NCBI Official Full Name
Transcription factor SOX-2
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 2
NCBI Official Symbol
SOX2
NCBI Official Synonym Symbols
ANOP3; MCOPS3
NCBI Protein Information
transcription factor SOX-2; transcription factor SOX2; SRY-related HMG-box gene 2
UniProt Protein Name
Transcription factor SOX-2
UniProt Gene Name
SOX2
UniProt Entry Name
SOX2_HUMAN
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Product Notes
The SOX2 sox2 (Catalog #AAA45727) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOX2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SOX2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SOX2 sox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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