WB (Western Blot)
(Western blot analysis of SPRYD2 in rat brain tissue lysate with SPRYD2 antibody at (A) 1 and (B) 2 ug/mL)
Rabbit SPRYD2 Polyclonal Antibody | anti-SPRYD2 antibody
SPRYD2 Antibody
Gene Names
CMYA5; SPRYD2; TRIM76; C5orf10
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
SPRYD2, Antibody; SPRYD2 Antibody; SPRY domain-containing protein 2, cardiomyopathy-associated protein 5, CMYA5, dystrobrevin-binding protein 2, DTNBP2, TRIM76; anti-SPRYD2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
4069
Applicable Applications for anti-SPRYD2 antibody
WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the carboxy terminus of human SPRYD2.
Target Name
SPRYD2
Preparation and Storage
Can be stored at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
WB (Western Blot)
(Western blot analysis of SPRYD2 in rat brain tissue lysate with SPRYD2 antibody at (A) 1 and (B) 2 ug/mL)
WB (Western Blot)
(Western blot analysis of SPRYD2 in rat brain tissue lysate with SPRYD2 antibody at (A) 1 and (B) 2 ug/mL)
Related Product Information for anti-SPRYD2 antibody
SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
Product Categories/Family for anti-SPRYD2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cardiomyopathy-associated protein 5
NCBI Official Synonym Full Names
cardiomyopathy associated 5
NCBI Official Symbol
CMYA5
NCBI Official Synonym Symbols
SPRYD2; TRIM76; C5orf10
NCBI Protein Information
cardiomyopathy-associated protein 5
UniProt Protein Name
Cardiomyopathy-associated protein 5
UniProt Gene Name
CMYA5
UniProt Synonym Gene Names
C5orf10; DTNBP2; SPRYD2; TRIM76
UniProt Entry Name
CMYA5_HUMAN
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Product Notes
The SPRYD2 cmya5 (Catalog #AAA303770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPRYD2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SPRYD2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SPRYD2 cmya5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPRYD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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