WB (Western Blot)
(Anti-SUSD2 Antibody (C-term) at 1:1000 dilution + WiDr whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 90 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human SUSD2 Polyclonal Antibody | anti-SUSD2 antibody
SUSD2 Antibody (C-term)
Gene Names
SUSD2; BK65A6.2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Synonyms
SUSD2, Antibody; SUSD2 Antibody (C-term); Sushi domain-containing protein 2; SUSD2; anti-SUSD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SUSD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 716-745 amino acids from the C-terminal region of human SUSD2.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applicable Applications for anti-SUSD2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Region
716-745
Function
May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed: ). May play a role in breast tumorigenesis (PubMed:).
Cellular Location
Cell membrane; Single-pass type I membrane protein. Note=SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.
Tissue Location
Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403)
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Anti-SUSD2 Antibody (C-term) at 1:1000 dilution + WiDr whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 90 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-SUSD2 Antibody (C-term) at 1:1000 dilution + WiDr whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 90 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
IHC (Immunohistochemistry)
(SUSD2 Antibody (C-term) (AAA284141) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SUSD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemistry)
(SUSD2 Antibody (C-term) (AAA284141) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SUSD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-SUSD2 antibody
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
Dunham, I., et al. Nature 402(6761):489-495(1999)
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
Dunham, I., et al. Nature 402(6761):489-495(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
90208
NCBI Official Full Name
sushi domain-containing protein 2
NCBI Official Synonym Full Names
sushi domain containing 2
NCBI Official Symbol
SUSD2
NCBI Official Synonym Symbols
BK65A6.2
NCBI Protein Information
sushi domain-containing protein 2
UniProt Protein Name
Sushi domain-containing protein 2
UniProt Gene Name
SUSD2
UniProt Entry Name
SUSD2_HUMAN
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Product Notes
The SUSD2 susd2 (Catalog #AAA284141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SUSD2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SUSD2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SUSD2 susd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUSD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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