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IF (Immunofluorescence)
(Immunofluorescence analysis of Rat Kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
Rabbit Tamm Horsfall Glycoprotein Polyclonal Antibody | anti-UMOD antibody
Tamm Horsfall Glycoprotein Rabbit pAb
Gene Names
UMOD; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
Tamm Horsfall Glycoprotein, Antibody; Tamm Horsfall Glycoprotein Rabbit pAb; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADTKD1; ADMCKD2; anti-UMOD antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
Liquid
PBS with 0.05% proclin300, 50% glycerol, pH7.3.
PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Applicable Applications for anti-UMOD antibody
ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)
Positive Samples
Mouse kidney
Cellular Location
apical plasma membrane, basolateral plasma membrane, cell surface, ciliary membrane, cilium, endoplasmic reticulum, extracellular exosome, extracellular space, Golgi lumen, spindle pole
Research Area
Cell Biology Developmental Biology
Immunogen
Recombinant protein of human Tamm Horsfall Glycoprotein.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Ship: Ice Pack
Ship: Ice Pack
IF (Immunofluorescence)
(Immunofluorescence analysis of Rat Kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Rat Kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Mouse kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Mouse kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Human kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Human kidney using Tamm Horsfall Glycoprotein Rabbit pAb (AAA282413) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining.)
WB (Western Blot)
(Western blot analysis of Mouse kidney, using Tamm Horsfall Glycoprotein antibody (AAA282413) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.)
WB (Western Blot)
(Western blot analysis of Mouse kidney, using Tamm Horsfall Glycoprotein antibody (AAA282413) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.)
Related Product Information for anti-UMOD antibody
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
Product Categories/Family for anti-UMOD antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,761 Da
NCBI Official Full Name
uromodulin isoform a preproprotein
NCBI Official Synonym Full Names
uromodulin
NCBI Official Symbol
UMOD
NCBI Official Synonym Symbols
THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
NCBI Protein Information
uromodulin; uromucoid; Tamm-Horsfall urinary glycoprotein
UniProt Protein Name
Uromodulin
UniProt Gene Name
UMOD
UniProt Synonym Gene Names
THP
UniProt Entry Name
UROM_HUMAN
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Product Notes
The UMOD umod (Catalog #AAA282413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tamm Horsfall Glycoprotein Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tamm Horsfall Glycoprotein can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the UMOD umod for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tamm Horsfall Glycoprotein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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