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IF (Immunofluorescence)
(Immunofluorescence analysis of Mouse brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100. Blue: DAPI for nuclear staining.)
Rabbit Tau-Ser416 Polyclonal Antibody | anti-Tau-Ser416 antibody
Phospho-Tau-Ser416 Rabbit pAb
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
Tau-Ser416, Antibody; Phospho-Tau-Ser416 Rabbit pAb; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Tau; anti-Tau-Ser416 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Applicable Applications for anti-Tau-Ser416 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A phospho specific peptide corresponding to residues surrounding Ser416 of human Tau.
Positive Samples
NIH/3T3
Cellular Location
Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, axon, cytoskeleton, cytosol
Research Area
Protein phosphorylation
Signal Transduction MAPK-P38 Signaling Pathway
Signal Transduction MAPK-P38 Signaling Pathway
Cell Biology & Developmental Biology Cytoskeleton Microtubules
Neuroscience Neuro degenerative Diseases Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Neuroscience Cell Type Marker Neural Stem Cell marker
Neuroscience Cell Type Marker Neuron marker
Neuroscience Cell Type Marker Axon marker
Catalog Proteins Drug Targets
Signal Transduction MAPK-P38 Signaling Pathway
Signal Transduction MAPK-P38 Signaling Pathway
Cell Biology & Developmental Biology Cytoskeleton Microtubules
Neuroscience Neuro degenerative Diseases Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Neuroscience Cell Type Marker Neural Stem Cell marker
Neuroscience Cell Type Marker Neuron marker
Neuroscience Cell Type Marker Axon marker
Catalog Proteins Drug Targets
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of Mouse brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100. Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Mouse brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100. Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Rat brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100. Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Rat brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100. Blue: DAPI for nuclear staining.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100 (40x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain using Phospho-Tau-Ser416 Rabbit pAb (AAA282185) at dilution of 1:100 (40x lens).)
WB (Western Blot)
(Western blot analysis of extracts of NIH/3T3 cells, using Phospho-Tau-Ser416 pAb (AAA282185) at 1:1000 dilution or Tau antibody (A0002).NIH/3T3 cells were treated by CIP(20uL/400ul) at 37 degree C for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (RM00020).Exposure time: 60s.)
WB (Western Blot)
(Western blot analysis of extracts of NIH/3T3 cells, using Phospho-Tau-Ser416 pAb (AAA282185) at 1:1000 dilution or Tau antibody (A0002).NIH/3T3 cells were treated by CIP(20uL/400ul) at 37 degree C for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (RM00020).Exposure time: 60s.)
Related Product Information for anti-Tau-Ser416 antibody
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Product Categories/Family for anti-Tau-Ser416 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78,928 Da
NCBI Official Full Name
microtubule-associated protein tau isoform 6
NCBI Official Synonym Full Names
microtubule-associated protein tau
NCBI Official Symbol
MAPT
NCBI Official Synonym Symbols
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
NCBI Protein Information
microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1
UniProt Protein Name
Microtubule-associated protein tau
UniProt Gene Name
MAPT
UniProt Synonym Gene Names
MAPTL; MTBT1; TAU; PHF-tau
UniProt Entry Name
TAU_HUMAN
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Product Notes
The Tau-Ser416 mapt (Catalog #AAA282185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-Tau-Ser416 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tau-Ser416 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Tau-Ser416 mapt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tau-Ser416, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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