IHC (Immunohiostchemistry)
(Detection of human TDP1 by immunohistochemistry. Sample: FFPE section of human ovarian tumor. Antibody: Affinity purified rabbit anti-TDP1 (Cat. No. AAA213954) used at a dilution of 1:250. Detection: DAB)
Rabbit anti-Human TDP1 Polyclonal Antibody | anti-TDP1 antibody
Rabbit anti-TDP1 IHC Antibody, Affinity Purified
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
TDP1, Antibody; Rabbit anti-TDP1 IHC Antibody, Affinity Purified; tyrosyl-DNA phosphodiesterase 1; tyr-DNA phosphodiesterase 1; Tyrosyl-DNA phosphodiesterase 1; anti-TDP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
250ug/ml (varies by lot)
Applicable Applications for anti-TDP1 antibody
IHC (Immunohistochemistry)
Predicted Reactivity
Orangutan, Gorilla, Chimpanzee
Immunogen
Between 1 and 50
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IHC (Immunohiostchemistry)
(Detection of human TDP1 by immunohistochemistry. Sample: FFPE section of human ovarian tumor. Antibody: Affinity purified rabbit anti-TDP1 (Cat. No. AAA213954) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human TDP1 by immunohistochemistry. Sample: FFPE section of human ovarian tumor. Antibody: Affinity purified rabbit anti-TDP1 (Cat. No. AAA213954) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human TDP1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TDP1 (Cat. No. AAA213954) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human TDP1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TDP1 (Cat. No. AAA213954) used at a dilution of 1:250. Detection: DAB)
Related Product Information for anti-TDP1 antibody
Tyrosyl-DNA phosphodiesterase 1 (TDP1) is an enzyme that participates in the repair of DNA strand breaks associated with topoisomerase 1 (Top1) complexes. TDP1 catalyzes the removal of Top1 from DNA via the hydrolysis of the phosphodiester bond between the tyrosine residue of Top1 and the 3' phosphate of DNA. Removal of Top1 is then followed by DNA repair. TDP1 has been proposed to play more general roles in DNA damage repair independent of the Top1 complex. TDP1 has been shown to associate with DNA ligase IIIalpha, a component of the DNA single-stranded break repair (SSBR) machinery. It is also able to remove glycolate from 3'-phosphoglycolate termini of double-stranded breaks and a variety of other 3'- adducts. Defects in TDP1 are associated with spinocerebellar ataxia autosomal recessive with axonal neuropathy (SCAN1), a disease associated with peripheral axonal motor and sensory neuropathy and distal muscular atrophy.
Product Categories/Family for anti-TDP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,630 Da
NCBI Official Full Name
tyrosyl-DNA phosphodiesterase 1
NCBI Official Synonym Full Names
tyrosyl-DNA phosphodiesterase 1
NCBI Official Symbol
TDP1
NCBI Protein Information
tyrosyl-DNA phosphodiesterase 1; tyr-DNA phosphodiesterase 1
UniProt Protein Name
Tyrosyl-DNA phosphodiesterase 1
UniProt Gene Name
TDP1
UniProt Synonym Gene Names
Tyr-DNA phosphodiesterase 1
UniProt Entry Name
TYDP1_HUMAN
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Product Notes
The TDP1 tdp1 (Catalog #AAA213954) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-TDP1 IHC Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TDP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TDP1 tdp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TDP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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