IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM5 in human bladder tissue with TEM5 antibody at 5 ug/mL.)
Rabbit TEM5 Polyclonal Antibody | anti-TEM5 antibody
TEM5 Antibody
Gene Names
ADGRA2; TEM5; GPR124
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
TEM5, Antibody; TEM5 Antibody; Tumor endothelial marker 5, G protein-coupled receptor 124, GPR124; anti-TEM5 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1338
Applicable Applications for anti-TEM5 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide near the center of human TEM5.
Target Name
TEM5
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM5 in human bladder tissue with TEM5 antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM5 in human bladder tissue with TEM5 antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of TEM5 in rat kidney tissue lysate with TEM5 antibody at (A) 2 ug/ml and (B) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of TEM5 in rat kidney tissue lysate with TEM5 antibody at (A) 2 ug/ml and (B) 4 ug/mL.)
Related Product Information for anti-TEM5 antibody
Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
Product Categories/Family for anti-TEM5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,530 Da
NCBI Official Full Name
G-protein coupled receptor 124
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor A2
NCBI Official Symbol
ADGRA2
NCBI Official Synonym Symbols
TEM5; GPR124
NCBI Protein Information
G-protein coupled receptor 124
UniProt Protein Name
G-protein coupled receptor 124
UniProt Gene Name
GPR124
UniProt Synonym Gene Names
KIAA1531; TEM5
UniProt Entry Name
GP124_HUMAN
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Product Notes
The TEM5 gpr124 (Catalog #AAA301925) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TEM5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TEM5 gpr124 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEM5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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