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product-image-AAA40500_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of TESPA1 in A431 cells with TESPA1 antibody at 20 μg/mL.)

Rabbit anti-Human TESPA1 Polyclonal Antibody | anti-TESPA1 antibody

TESPA1 Antibody

Gene Names
TESPA1; HSPC257; KIAA0748
Reactivity
Human
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
TESPA1 antibody is affinity chromatography purified via peptide column.
Synonyms
TESPA1, Antibody; TESPA1 Antibody; TESPA1; HSPC257; KIAA0748; Protein TESPA1; Thymocyte-expressed positive selection-associated protein 1; thymocyte expressed, positive selection associated 1; anti-TESPA1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TESPA1 antibody is human specific. At least three isoforms TESPA1 are known to exist.
Purity/Purification
TESPA1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid ; TESPA1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Sequence Length
521
Applicable Applications for anti-TESPA1 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen
TESPA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human TESPA1.
The immunogen is located within amino acids 20 - 70 of TESPA1.
Preparation and Storage
TESPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of TESPA1 in A431 cells with TESPA1 antibody at 20 μg/mL.)

product-image-AAA40500_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of TESPA1 in A431 cells with TESPA1 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of TESPA1 in A431 cells with TESPA1 antibody at 5 μg/mL.)

product-image-AAA40500_ICC13.jpg ICC (Immunocytochemistry) (Immunocytochemistry of TESPA1 in A431 cells with TESPA1 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of TESPA1 in A431 cell lysate with TESPA1 antibody at 1 μg/ml.)

product-image-AAA40500_WB15.gif WB (Western Blot) (Western blot analysis of TESPA1 in A431 cell lysate with TESPA1 antibody at 1 μg/ml.)
Related Product Information for anti-TESPA1 antibody
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development (1). TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species (2). TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage (3). TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus (1,4).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 57 kDa

Observed: 60 kDa
NCBI Official Full Name
protein TESPA1 isoform 1
NCBI Official Synonym Full Names
thymocyte expressed, positive selection associated 1
NCBI Official Symbol
TESPA1
NCBI Official Synonym Symbols
HSPC257; KIAA0748
NCBI Protein Information
protein TESPA1; thymocyte-expressed positive selection-associated protein 1
UniProt Protein Name
Protein TESPA1
UniProt Gene Name
TESPA1
UniProt Synonym Gene Names
KIAA0748
UniProt Entry Name
TESP1_HUMAN

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Product Notes

The TESPA1 tespa1 (Catalog #AAA40500) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TESPA1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TESPA1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TESPA1 tespa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TESPA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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