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product-image-AAA173824_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded Human kidney tissue using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:200.)

Rabbit TLE1/2/3/4 Polyclonal Antibody | anti-TLE1/2/3/4 antibody

TLE1/2/3/4 Polyclonal Antibody

Gene Names
TLE1; ESG; ESG1; GRG1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
TLE1/2/3/4, Antibody; TLE1/2/3/4 Polyclonal Antibody; similar to transducin-like enhancer of split 1/2/3/4; anti-TLE1/2/3/4 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
780
Applicable Applications for anti-TLE1/2/3/4 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Synthesized peptide derived from TLE1/2/3/4
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded Human kidney tissue using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:200.)

product-image-AAA173824_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded Human kidney tissue using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:200.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:200.)

product-image-AAA173824_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:200.)

WB (Western Blot)

(Western Blot analysis of A549, 3T3, Mouse liver, SH-SY5Y, K562, Hela, 293T using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:2000.)

product-image-AAA173824_WB15.jpg WB (Western Blot) (Western Blot analysis of A549, 3T3, Mouse liver, SH-SY5Y, K562, Hela, 293T using TLE1/2/3/4 Polyclonal Antibody at dilution of 1:2000.)
Related Product Information for anti-TLE1/2/3/4 antibody
TLE1 (Transducin Like Enhancer Of Split 1) is a Protein Coding gene. Diseases associated with TLE1 include Synovium Cancer and Spindle Cell Liposarcoma. Among its related pathways are Signaling by Wnt and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include identical protein binding and transcription factor binding. An important paralog of this gene is TLE4. TLE2 (Transducin Like Enhancer Of Split 2) is a Protein Coding gene. Among its related pathways are Signaling by Wnt and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transcription corepressor activity. An important paralog of this gene is TLE1. TLE3 (Transducin Like Enhancer Of Split 3) is a Protein Coding gene. Among its related pathways are Signaling by Wnt and CDK-mediated phosphorylation and removal of Cdc6. An important paralog of this gene is TLE4.This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. TLE4 (Transducin Like Enhancer Of Split 4) is a Protein Coding gene. Among its related pathways are Signaling by Wnt and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include chromatin binding and transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is TLE1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90kDa
NCBI Official Full Name
transducin-like enhancer protein 1 isoform 1
NCBI Official Synonym Full Names
transducin like enhancer of split 1
NCBI Official Symbol
TLE1
NCBI Official Synonym Symbols
ESG; ESG1; GRG1
NCBI Protein Information
transducin-like enhancer protein 1
UniProt Protein Name
Transducin-like enhancer protein 1
UniProt Gene Name
TLE1
UniProt Synonym Gene Names
ESG1

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Product Notes

The TLE1/2/3/4 tle1 (Catalog #AAA173824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLE1/2/3/4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TLE1/2/3/4 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TLE1/2/3/4 tle1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLE1/2/3/4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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