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IF (Immunofluorescence)
(Immunofluorescence of TLR4 in human spleen tissue with TLR4 antibody at 20 μg/ml.Green: TLR4 Antibody (3141)Blue: DAPI staining)
Rabbit anti-Human TLR4 Polyclonal Antibody | anti-TLR4 antibody
TLR4 Antibody
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Reactivity
Human
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
TLR4 Antibody is affinity chromatography purified via peptide column.
Synonyms
TLR4, Antibody; TLR4 Antibody; TLR4; TOLL; CD284; TLR-4; ARMD10; Toll-like receptor 4; hToll; toll-like receptor 4; anti-TLR4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TLR4 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
839
Applicable Applications for anti-TLR4 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.
Buffer
TLR4 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TLR4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of TLR4 in human spleen tissue with TLR4 antibody at 20 μg/ml.Green: TLR4 Antibody (3141)Blue: DAPI staining)
IF (Immunofluorescence)
(Immunofluorescence of TLR4 in human spleen tissue with TLR4 antibody at 20 μg/ml.Green: TLR4 Antibody (3141)Blue: DAPI staining)
IHC (Immunohistochemisry)
(Immunohistochemistry of TLR4 in human spleen tissue with TLR4 antibody at 2.5 μg/ml.)
IHC (Immunohistochemisry)
(Immunohistochemistry of TLR4 in human spleen tissue with TLR4 antibody at 2.5 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of TLR4 in K562 cells with TLR4 antibody at 2 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of TLR4 in K562 cells with TLR4 antibody at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of TLR4 in human small intestine lysate with TLR4 antibody at (A) 2 and (B) 4 μg/mL.)
WB (Western Blot)
(Western blot analysis of TLR4 in human small intestine lysate with TLR4 antibody at (A) 2 and (B) 4 μg/mL.)
Related Product Information for anti-TLR4 antibody
TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73,301 Da
NCBI Official Full Name
toll-like receptor 4 isoform A
NCBI Official Synonym Full Names
toll-like receptor 4
NCBI Official Symbol
TLR4
NCBI Official Synonym Symbols
TOLL; CD284; TLR-4; ARMD10
NCBI Protein Information
toll-like receptor 4; hToll; homolog of Drosophila toll
UniProt Protein Name
Toll-like receptor 4
UniProt Gene Name
TLR4
UniProt Entry Name
TLR4_HUMAN
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Product Notes
The TLR4 tlr4 (Catalog #AAA39778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TLR4 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TLR4 tlr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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