IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using AAA229260 at dilution of 1:100)
Rabbit anti-Human TLR6 Polyclonal Antibody | anti-TLR6 antibody
TLR6 Antibody
Gene Names
TLR6; CD286
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity Purified
Synonyms
TLR6, Antibody; TLR6 Antibody; Toll-like receptor 6; TLR6; CD_antigen: CD286; anti-TLR6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
796
Applicable Applications for anti-TLR6 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant human Toll-like receptor 6 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5658 / sc-5657 / sc-30001
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using AAA229260 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using AAA229260 at dilution of 1:100)
WB (Western Blot)
(Western blotAll lanes: TLR6 antibody at 5ug/ml+ Jurkat whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 92,56 kDaObserved band size: 92 kDa)
WB (Western Blot)
(Western blotAll lanes: TLR6 antibody at 5ug/ml+ Jurkat whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 92,56 kDaObserved band size: 92 kDa)
Related Product Information for anti-TLR6 antibody
Participates in the innate immune response to bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2 (PubMed:11441107). In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,828 Da
NCBI Official Full Name
toll-like receptor 6
NCBI Official Synonym Full Names
toll like receptor 6
NCBI Official Symbol
TLR6
NCBI Official Synonym Symbols
CD286
NCBI Protein Information
toll-like receptor 6
UniProt Protein Name
Toll-like receptor 6
UniProt Gene Name
TLR6
UniProt Entry Name
TLR6_HUMAN
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Product Notes
The TLR6 tlr6 (Catalog #AAA229260) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TLR6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TLR6 tlr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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