Rabbit anti-Human, Mouse TLR7 Polyclonal Antibody | anti-Tlr7 antibody

TLR7 Antibody

Cat. Num. AAA39327

• Reactivity: Human, Mouse
• Applications: Immunocytochemistry, Western Blot, ELISA
• Purity: TLR7 Antibody is affinity chromatography purified via peptide column.
• Synonyms: TLR7, Antibody; TLR7 Antibody; TLR7; Toll-like receptor 7; toll-like receptor 7; anti-Tlr7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TLR7 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1050

• Applicable Applications for anti-Tlr7 antibody: ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7.
• Buffer: TLR7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TLR7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ICC (Immunocytochemistry)

(Immunocytochemistry staining of Daudi cells using TLR7 antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of TLR7 in Daudi cell lysates with TLR7 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)

Related Product Information for anti-Tlr7 antibody

TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

NCBI and Uniprot Product Information

• NCBI GI #: 18875360
• NCBI GeneID: 170743
• NCBI Accession #: NP_573474
• NCBI GenBank Nucleotide #: NM_133211.4
• UniProt Accession #: P58681; Q923I1
• Molecular Weight: Predicted: 116 kDa; ; Observed: 135 kDa
• NCBI Official Full Name: toll-like receptor 7 isoform a
• NCBI Official Synonym Full Names: toll-like receptor 7
• NCBI Official Symbol: Tlr7
• NCBI Protein Information: toll-like receptor 7
• UniProt Protein Name: Toll-like receptor 7
• UniProt Gene Name: Tlr7
• UniProt Entry Name: TLR7_MOUSE