Rabbit TMEM38A Polyclonal Antibody | anti-TMEM38A antibody

TMEM38A Antibody

Cat. Num. AAA39460

• Gene Names: TMEM38A; TRICA; TRIC-A
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: TMEM38A Antibody is affinity chromatography purified via peptide column.
• Synonyms: TMEM38A, Antibody; TMEM38A Antibody; TMEM38A; TRICA; TRIC-A; Trimeric intracellular cation channel type A; Transmembrane protein 38A; transmembrane protein 38A; anti-TMEM38A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TMEM38A Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 299

• Applicable Applications for anti-TMEM38A antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TMEM38A antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A.
• Buffer: TMEM38A Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TMEM38A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TMEM38A in mouse skeletal muscle tissue with TMEM38A antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of TMEM38A in rat skeletal muscle tissue lysate with TMEM38A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-TMEM38A antibody

TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.

NCBI and Uniprot Product Information

• NCBI GI #: 12654711
• NCBI GeneID: 79041
• UniProt Accession #: Q9H6F2; A8K9P9
• Molecular Weight: 33,260 Da
• NCBI Official Full Name: Transmembrane protein 38A
• NCBI Official Synonym Full Names: transmembrane protein 38A
• NCBI Official Symbol: TMEM38A
• NCBI Official Synonym Symbols: TRICA; TRIC-A
• NCBI Protein Information: trimeric intracellular cation channel type A
• UniProt Protein Name: Trimeric intracellular cation channel type A
• UniProt Gene Name: TMEM38A
• UniProt Synonym Gene Names: TRIC-A; TRICA
• UniProt Entry Name: TM38A_HUMAN