WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
Rabbit anti-Human TMEPAI Polyclonal Antibody | anti-TMEPAI antibody
TMEPAI Polyclonal Antibody
Gene Names
PMEPA1; STAG1; TMEPAI
Reactivity
Human
Applications
Western Blot
Synonyms
TMEPAI, Antibody; TMEPAI Polyclonal Antibody; Transmembrane prostate androgen-induced protein (Solid tumor-associated 1 protein); anti-TMEPAI antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Applicable Applications for anti-TMEPAI antibody
WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
Related Product Information for anti-TMEPAI antibody
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal (PubMed:24627487). Also involved in down-regulation of the androgen receptor (AR), enhancing ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4 (PubMed:18703514).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,609 Da
NCBI Official Full Name
transmembrane prostate androgen-induced protein isoform d
NCBI Official Synonym Full Names
prostate transmembrane protein, androgen induced 1
NCBI Official Symbol
PMEPA1
NCBI Official Synonym Symbols
STAG1; TMEPAI
NCBI Protein Information
transmembrane prostate androgen-induced protein; solid tumor-associated 1 protein; transmembrane, prostate androgen induced RNA
UniProt Protein Name
Transmembrane prostate androgen-induced protein
UniProt Gene Name
PMEPA1
UniProt Synonym Gene Names
STAG1; TMEPAI
UniProt Entry Name
PMEPA_HUMAN
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Product Notes
The TMEPAI pmepa1 (Catalog #AAA296517) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEPAI Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMEPAI can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the TMEPAI pmepa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEPAI, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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