IHC (Immunohiostchemistry)
(TMUB1 antibody (Center) (AAA287877) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TMUB1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit TMUB1 Polyclonal Antibody | anti-TMUB1 antibody
TMUB1 Antibody (Center)
Gene Names
TMUB1; DULP; SB144; C7orf21
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TMUB1, Antibody; TMUB1 Antibody (Center); Transmembrane and ubiquitin-like domain-containing protein 1; Dendritic cell-derived ubiquitin-like protein; DULP; Hepatocyte odd protein shuttling protein; Ubiquitin-like protein SB144; TMUB1; C7orf21; HOPS; anti-TMUB1 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
This TMUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human TMUB1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
112-141
Sequence Length
246
Applicable Applications for anti-TMUB1 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Preparation and Storage
For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(TMUB1 antibody (Center) (AAA287877) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TMUB1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(TMUB1 antibody (Center) (AAA287877) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TMUB1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(TMUB1 Antibody (Center) (AAA287877) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the TMUB1 antibody detected TMUB1 protein (arrow).)
WB (Western Blot)
(TMUB1 Antibody (Center) (AAA287877) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the TMUB1 antibody detected TMUB1 protein (arrow).)
Related Product Information for anti-TMUB1 antibody
Function
Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as a negative regulator of hepatocyte growth during regeneration (By similarity).
Cellular Location
Membrane {ECO:0000250|UniProtKB:Q9JMG3}; Multi- pass membrane protein {ECO:0000250|UniProtKB:Q9JMG3}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9JMG3}. Recycling endosome {ECO:0000250|UniProtKB:Q53AQ4}. Cytoplasm {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus {ECO:0000250|UniProtKB:Q9JMG3} Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9JMG3}
Tissue Location
Ubiquitously expressed with highest levels in mammary and thyroid glands, bone marrow and spleen; limited expression in cardiac, pancreatic and ovarian tissues.
Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as a negative regulator of hepatocyte growth during regeneration (By similarity).
Cellular Location
Membrane {ECO:0000250|UniProtKB:Q9JMG3}; Multi- pass membrane protein {ECO:0000250|UniProtKB:Q9JMG3}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9JMG3}. Recycling endosome {ECO:0000250|UniProtKB:Q53AQ4}. Cytoplasm {ECO:0000250|UniProtKB:Q9JMG3}. Nucleus {ECO:0000250|UniProtKB:Q9JMG3} Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9JMG3}
Tissue Location
Ubiquitously expressed with highest levels in mammary and thyroid glands, bone marrow and spleen; limited expression in cardiac, pancreatic and ovarian tissues.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26261
NCBI Official Full Name
transmembrane and ubiquitin-like domain-containing protein 1
NCBI Official Synonym Full Names
transmembrane and ubiquitin-like domain containing 1
NCBI Official Symbol
TMUB1
NCBI Official Synonym Symbols
DULP; SB144; C7orf21
NCBI Protein Information
transmembrane and ubiquitin-like domain-containing protein 1
UniProt Protein Name
Transmembrane and ubiquitin-like domain-containing protein 1
UniProt Gene Name
TMUB1
UniProt Synonym Gene Names
C7orf21; DULP; HOPS; DULP
UniProt Entry Name
TMUB1_HUMAN
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Product Notes
The TMUB1 tmub1 (Catalog #AAA287877) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 112-141. The TMUB1 Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's TMUB1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TMUB1 tmub1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMUB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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