IHC (Immunohistochemisry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.)
Rabbit anti-Human, mouse TNF12 Polyclonal Antibody | anti-TNFSF12 antibody
TNF12 Antibody
Gene Names
TNFSF12; APO3L; DR3LG; TWEAK
Reactivity
Human, mouse
Applications
Immunohistochemistry, Immunofluorescence, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TNF12, Antibody; TNF12 Antibody; Tumor necrosis factor ligand superfamily member 12; APO3 ligand; TNF-related weak inducer of apoptosis; TWEAK; membrane form; secreted form; TNFSF12; APO3L; DR3LG; anti-TNFSF12 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Positions
62-90
Sequence Length
330
Applicable Applications for anti-TNFSF12 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.)
IHC (Immunohistochemisry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells, using TNF12 antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells, using TNF12 antibody.)
WB (Western Blot)
(Western blot analysis of lysates from 293,HUVEC cell line (from left to right),using TNF12 Antibody(AAA285578). AAA285578 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from 293,HUVEC cell line (from left to right),using TNF12 Antibody(AAA285578). AAA285578 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.)
Related Product Information for anti-TNFSF12 antibody
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Product Categories/Family for anti-TNFSF12 antibody
References
Chicheportiche Y.,et al.J. Biol. Chem. 272:32401-32410(1997).
Marsters S.A.,et al.Curr. Biol. 8:525-528(1998).
Pradet-Balade B.,et al.EMBO J. 21:5711-5720(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Marsters S.A.,et al.Curr. Biol. 8:525-528(1998).
Pradet-Balade B.,et al.EMBO J. 21:5711-5720(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Zody M.C.,et al.Nature 440:1045-1049(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27216
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 12 proprotein
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 12
NCBI Official Symbol
TNFSF12
NCBI Official Synonym Symbols
APO3L; DR3LG; TWEAK
NCBI Protein Information
tumor necrosis factor ligand superfamily member 12
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 12
UniProt Gene Name
TNFSF12
UniProt Synonym Gene Names
APO3L; DR3LG; TWEAK
UniProt Entry Name
TNF12_HUMAN
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Product Notes
The TNFSF12 tnfsf12 (Catalog #AAA285578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 62-90. The TNF12 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TNF12 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TNFSF12 tnfsf12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNF12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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