Rabbit TRESK Polyclonal Antibody | anti-KCNK18 antibody

TRESK Antibody

Cat. Num. AAA39929

• Gene Names: KCNK18; TRIK; MGR13; TRESK; TRESK2; K2p18.1; TRESK-2
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: TRESK Antibody is affinity chromatography purified via peptide column.
• Synonyms: TRESK, Antibody; TRESK Antibody; TRESK; TRIK; MGR13; TRESK2; K2p18.1; TRESK-2; Potassium channel subfamily K member 18; TWIK-related individual potassium channel; potassium channel, subfamily K, member 18; anti-KCNK18 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TRESK Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 384

• Applicable Applications for anti-KCNK18 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK.
• Buffer: TRESK Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TRESK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TRESK in Rat Brain cells with TRESK antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of TRESK in rat brain tissue with TRESK antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of TRESK in rat brain tissue lysate with TRESK antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-KCNK18 antibody

TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

NCBI and Uniprot Product Information

• NCBI GI #: 32469495
• NCBI GeneID: 338567
• NCBI Accession #: NP_862823
• NCBI GenBank Nucleotide #: NM_181840.1
• UniProt Accession #: Q7Z418; Q5SQQ8
• Molecular Weight: 43,671 Da
• NCBI Official Full Name: potassium channel subfamily K member 18
• NCBI Official Synonym Full Names: potassium channel, two pore domain subfamily K, member 18
• NCBI Official Symbol: KCNK18
• NCBI Official Synonym Symbols: TRIK; MGR13; TRESK; TRESK2; K2p18.1; TRESK-2
• NCBI Protein Information: potassium channel subfamily K member 18; TWIK-related individual K+ channel; TWIK-related spinal cord K+ channel; TWIK-related individual potassium channel; potassium channel, subfamily K, member 18; TWIK-related spinal cord potassium channel
• UniProt Protein Name: Potassium channel subfamily K member 18
• UniProt Gene Name: KCNK18
• UniProt Synonym Gene Names: TRESK; TRIK
• UniProt Entry Name: KCNKI_HUMAN