Rabbit anti-Human TRRAP Polyclonal Antibody | anti-TRRAP antibody

TRRAP Antibody (C-term)

Cat. Num. AAA290533

• Reactivity: Human
• Applications: Western Blot
• Synonyms: TRRAP, Antibody; TRRAP Antibody (C-term); Purified Rabbit Polyclonal Antibody (Pab); Transformation/transcription domain-associated protein; 350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homolog; TRRAP; PAF400; anti-TRRAP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Ig
• Specificity: This TRRAP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3015-3049 amino acids from the C-terminal region of human TRRAP.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Length: 3859

• Applicable Applications for anti-TRRAP antibody: WB (Western Blot)
• Antigen Source: Human
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(All lanes : Anti-TRRAP Antibody (C-term) at 1:2000 dilutionLane 1: K562 whole cell lysatesLane 2: Hela whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 438 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

WB (Western Blot)

(Anti-TRRAP Antibody (C-term)at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 438 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-TRRAP antibody

Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1- like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

Product Categories/Family for anti-TRRAP antibody

Crown Antibodies

References

McMahon S.B.,et al.Cell 94:363-374(1998). Vassilev A.,et al.Mol. Cell 2:869-875(1998). Hillier L.W.,et al.Nature 424:157-164(2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Scherer S.W.,et al.Science 300:767-772(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 347360922
• NCBI GeneID: 8295
• NCBI Accession #: NP_001231509.1
• NCBI GenBank Nucleotide #: NM_001244580.1
• UniProt Accession #: Q9Y4A5; O75218; Q9Y631; Q9Y6H4; A4D265
• Molecular Weight: 437600
• NCBI Official Full Name: transformation/transcription domain-associated protein isoform 1
• UniProt Protein Name: Transformation/transcription domain-associated protein
• UniProt Gene Name: TRRAP
• UniProt Synonym Gene Names: PAF400; PAF350/400
• UniProt Entry Name: TRRAP_HUMAN