Rabbit anti-Human Tryptase-3 Polyclonal Antibody | anti-TPSD1 antibody

Tryptase-3 Polyclonal Antibody

Cat. Num. AAA173829

• Gene Names: TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Affinity Purification
• Synonyms: Tryptase-3, Antibody; Tryptase-3 Polyclonal Antibody; Tryptase delta (EC 3.4.21.59) (Delta-tryptase) (HmMCP-3-like tryptase III) (Mast cell mMCP-7-like) (Tryptase-3); anti-TPSD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Concentration: 1mg/mL (varies by lot)
• Sequence Length: 242

• Applicable Applications for anti-TPSD1 antibody: ELISA, IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Synthesized peptide derived from Tryptase-3
• Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
• Preparation and Storage: Store at -20 degree C. Avoid freeze / thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded Human skin tissue using Tryptase-3 Polyclonal Antibody at dilution of 1:200.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using Tryptase-3 Polyclonal Antibody at dilution of 1:200.)

WB (Western Blot)

(Western Blot analysis of HepG2 cells using Tryptase-3 Polyclonal Antibody at dilution of 1:800.)

Related Product Information for anti-TPSD1 antibody

TPSD1 (Tryptase Delta 1) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is TPSAB1.Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.

NCBI and Uniprot Product Information

• NCBI GI #: 11321636
• NCBI GeneID: 23430
• NCBI Accession #: NP_036349.1
• NCBI GenBank Nucleotide #: NM_012217.2
• UniProt Accession #: Q9BZJ3; O95824; Q8TDI6; Q96L36; Q96RZ5; Q9H2Y6; Q9UQI8
• Molecular Weight: Calculated Molecular Weight: 27kDa; Observed Molecular Weight: 26kDa
• NCBI Official Full Name: tryptase delta
• NCBI Official Synonym Full Names: tryptase delta 1
• NCBI Official Symbol: TPSD1
• NCBI Official Synonym Symbols: MCP7L1; MMCP-7L; MCP7-LIKE
• NCBI Protein Information: tryptase delta
• UniProt Protein Name: Tryptase delta
• UniProt Gene Name: TPSD1