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WB (Western Blot)
(Detection of human and mouse TS by western blot. Samples: Whole cell lysate (50 ug) from Jurkat, HEK293T, HeLa, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-TS antibody AAA212437 (lot AAA212437-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Rabbit anti-Human, Mouse TS Polyclonal Antibody | anti-TS antibody
Rabbit anti-TS Antibody, Affinity Purified
Gene Names
TYMS; TS; TMS; HST422
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
TS, Antibody; Rabbit anti-TS Antibody, Affinity Purified; TSase; TS; TMS; HST422; thymidylate synthase; Thymidylate synthase; thymidylate synthetase; anti-TS antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-TS antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Rat, Bovine, Dog, Rabbit, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee
Immunogen
Between 263 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human and mouse TS by western blot. Samples: Whole cell lysate (50 ug) from Jurkat, HEK293T, HeLa, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-TS antibody AAA212437 (lot AAA212437-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
WB (Western Blot)
(Detection of human and mouse TS by western blot. Samples: Whole cell lysate (50 ug) from Jurkat, HEK293T, HeLa, mouse TCMK-1, and mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-TS antibody AAA212437 (lot AAA212437-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human TS by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-TS antibody AAA212437 (lot AAA212437-1) used for IP at 6 ug/mg lysate. TS was also immunoprecipitated by rabbit anti-TS antibody BL14405. For blotting immunoprecipitated TS, AAA212437 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
IP (Immunoprecipitation)
(Detection of human TS by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-TS antibody AAA212437 (lot AAA212437-1) used for IP at 6 ug/mg lysate. TS was also immunoprecipitated by rabbit anti-TS antibody BL14405. For blotting immunoprecipitated TS, AAA212437 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
IHC (Immunohiostchemistry)
(Detection of mouse TS by immunohistochemistry. Samples: FFPE sections of mouse teratoma (left) and plasmacytoma (right). Antibody: Affinity purified rabbit anti-TS (Cat. No. AAA212437 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of mouse TS by immunohistochemistry. Samples: FFPE sections of mouse teratoma (left) and plasmacytoma (right). Antibody: Affinity purified rabbit anti-TS (Cat. No. AAA212437 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human TS by immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma (left) and lung cancer (right). Antibody: Affinity purified rabbit anti-TS (Cat. No. AAA212437 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human TS by immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma (left) and lung cancer (right). Antibody: Affinity purified rabbit anti-TS (Cat. No. AAA212437 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
Related Product Information for anti-TS antibody
Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].
Product Categories/Family for anti-TS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,140 Da
NCBI Official Full Name
thymidylate synthase
NCBI Official Synonym Full Names
thymidylate synthetase
NCBI Official Symbol
TYMS
NCBI Official Synonym Symbols
TS; TMS; HST422
NCBI Protein Information
thymidylate synthase; TSase
UniProt Protein Name
Thymidylate synthase
UniProt Gene Name
TYMS
UniProt Synonym Gene Names
TS; TS; TSase
UniProt Entry Name
TYSY_HUMAN
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Product Notes
The TS tyms (Catalog #AAA212437) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-TS Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TS can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the TS tyms for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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