WB (Western Blot)
(TSC2 Antibody (Center S1418/S1420) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TSC2 antibody detected the TSC2 protein (arrow).)
Rabbit anti-Human TSC2 Polyclonal Antibody | anti-TSC2 antibody
TSC2 Antibody (Center S1418/S1420)
Gene Names
TSC2; LAM; TSC4; PPP1R160
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TSC2, Antibody; TSC2 Antibody (Center S1418/S1420); Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4; anti-TSC2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1397-1426 amino acids from the Central region of human TSC2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
1397-1426
Sequence Length
1807
Applicable Applications for anti-TSC2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(TSC2 Antibody (Center S1418/S1420) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TSC2 antibody detected the TSC2 protein (arrow).)
WB (Western Blot)
(TSC2 Antibody (Center S1418/S1420) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TSC2 antibody detected the TSC2 protein (arrow).)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded H. brain section using TSC2 Antibody (Center S1418/S1420). AAA283945 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded H. brain section using TSC2 Antibody (Center S1418/S1420). AAA283945 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
Related Product Information for anti-TSC2 antibody
Mutations in this gene lead to tuberous sclerosis complex.
Its gene product is believed to be a tumor suppressor and is able
to stimulate specific GTPases. The protein associates with hamartin
in a cytosolic complex, possibly acting as a chaperone for
hamartin. Alternative splicing results in multiple transcript
variants encoding different isoforms.
Its gene product is believed to be a tumor suppressor and is able
to stimulate specific GTPases. The protein associates with hamartin
in a cytosolic complex, possibly acting as a chaperone for
hamartin. Alternative splicing results in multiple transcript
variants encoding different isoforms.
Product Categories/Family for anti-TSC2 antibody
References
Slattery, M.L., et al. Carcinogenesis 31(9):1604-1611(2010)
Larson, Y., et al. J. Biol. Chem. 285(32):24987-24998(2010)
Mehta, M.S., et al. Breast Cancer Res. Treat. (2010) In press :
Mieulet, V., et al. Trends Mol Med 16(7):329-335(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Larson, Y., et al. J. Biol. Chem. 285(32):24987-24998(2010)
Mehta, M.S., et al. Breast Cancer Res. Treat. (2010) In press :
Mieulet, V., et al. Trends Mol Med 16(7):329-335(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
200608
NCBI Official Full Name
tuberin isoform 1
NCBI Official Synonym Full Names
tuberous sclerosis 2
NCBI Official Symbol
TSC2
NCBI Official Synonym Symbols
LAM; TSC4; PPP1R160
NCBI Protein Information
tuberin
UniProt Protein Name
Tuberin
UniProt Gene Name
TSC2
UniProt Synonym Gene Names
TSC4
UniProt Entry Name
TSC2_HUMAN
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Product Notes
The TSC2 tsc2 (Catalog #AAA283945) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1397-1426. The TSC2 Antibody (Center S1418/S1420) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TSC2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TSC2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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