Rabbit UBC13 Polyclonal Antibody | anti-UBE2N antibody

UBC13 Antibody

Cat. Num. AAA39824

• Gene Names: UBE2N; UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: UBC13 Antibody is affinity chromatography purified via peptide column.
• Synonyms: UBC13, Antibody; UBC13 Antibody; UBC13; UbcH13; HEL-S-71; UbcH-ben; BLU; Ubiquitin-conjugating enzyme E2 N; Bendless-like ubiquitin-conjugating enzyme; ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); anti-UBE2N antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: UBC13 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 152

• Applicable Applications for anti-UBE2N antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: UBC13 antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human UBC13.
• Buffer: UBC13 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: UBC13 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohistochemistry)

(Immunohistochemistry of UBC13 in mouse thymus tissue with UBC13 antibody at 2.5 μg/ml.)

IF (Immunofluorescence)

(Immunofluorescence of UBC13 in Mouse Thymus cells with UBC13 antibody at 10 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of UBC13 in mouse thymus tissue with UBC13 antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of UBC13 in human small intestine cell lysates with UBC13 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)

Related Product Information for anti-UBE2N antibody

UBC13 Antibody: Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway. It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family. The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation.

NCBI and Uniprot Product Information

• NCBI GI #: 30582585
• NCBI GeneID: 7334
• UniProt Accession #: P61088; Q16781; Q53Y81
• Molecular Weight: 17,138 Da
• NCBI Official Full Name: ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
• NCBI Official Synonym Full Names: ubiquitin-conjugating enzyme E2N
• NCBI Official Symbol: UBE2N
• NCBI Official Synonym Symbols: UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13
• NCBI Protein Information: ubiquitin-conjugating enzyme E2 N; yeast UBC13 homolog; ubiquitin-protein ligase N; ubiquitin carrier protein N; epididymis secretory protein Li 71; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)
• UniProt Protein Name: Ubiquitin-conjugating enzyme E2 N
• UniProt Gene Name: UBE2N
• UniProt Synonym Gene Names: BLU
• UniProt Entry Name: UBE2N_HUMAN