IF (Immunofluorescence)
(Immunofluorescence of ULK3 in human brain tissue with ULK3 antibody at 20 μg/mL.)
Rabbit anti-Human ULK3 Polyclonal Antibody | anti-ULK3 antibody
ULK3 Antibody
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
ULK3 antibody is affinity chromatography purified via peptide column.
Synonyms
ULK3, Antibody; ULK3 Antibody; ULK3; Unc-51-like kinase 3; unc-51 like kinase 3; anti-ULK3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
ULK3 antibody is human specific. Multiple isoforms of ULK3 are known to exist.
Purity/Purification
ULK3 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
472
Applicable Applications for anti-ULK3 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ULK3 antibody was raised against a 19 amino acid peptide near the center of human ULK3.
Buffer
ULK3 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ULK3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of ULK3 in human brain tissue with ULK3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of ULK3 in human brain tissue with ULK3 antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ULK3 in human brain tissue with ULK3 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ULK3 in human brain tissue with ULK3 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of ULK3 in human brain tissue lysate with ULK3 antibody at (A) 0.5 and (B) 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of ULK3 in human brain tissue lysate with ULK3 antibody at (A) 0.5 and (B) 1 μg/ml.)
Related Product Information for anti-ULK3 antibody
ULK3 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK3, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK4, is highly conserved among eukaryotes (3). ULK3 has been shown to be a positive regulator of the Hedgehog signaling pathway by enhancing GLI1 and GLI2 transcriptional activity (4). Furthermore, ULK3 can also interact with SUFU, a protein required for the negative regulation of GLI proteins; this interaction blocks the autophosphorylation of ULK3 and blocks its ability to regulate the GLI proteins (5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 52 kDa
Observed: 52 kDa
Observed: 52 kDa
NCBI Official Full Name
serine/threonine-protein kinase ULK3
NCBI Official Synonym Full Names
unc-51 like kinase 3
NCBI Official Symbol
ULK3
NCBI Protein Information
serine/threonine-protein kinase ULK3
UniProt Protein Name
Serine/threonine-protein kinase ULK3
UniProt Gene Name
ULK3
UniProt Entry Name
ULK3_HUMAN
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Product Notes
The ULK3 ulk3 (Catalog #AAA40714) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ULK3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ULK3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ULK3 ulk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ULK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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