IHC (Immunohiostchemistry)
(Immunohistochemistry of Unc93b in human heart with Unc93b antibody at 2.5 ug/mL.)
Rabbit Unc93b Polyclonal Antibody | anti-Unc93b antibody
Unc93b Antibody
Gene Names
UNC93B1; IIAE1; UNC93; UNC93B; Unc-93B1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Unc93b, Antibody; Unc93b Antibody; Unc93b1, homolog of C. elegans Unc93; anti-Unc93b antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Multiple isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93a.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
505
Applicable Applications for anti-Unc93b antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide from near the amino terminus of human Unc93b.
Target Name
Unc93b
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Unc93b in human heart with Unc93b antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Unc93b in human heart with Unc93b antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Unc93b in human heart tissue lysate with Unc93b antibody at (A) 0.5 and (B) 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of Unc93b in human heart tissue lysate with Unc93b antibody at (A) 0.5 and (B) 1 ug/mL.)
Related Product Information for anti-Unc93b antibody
The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C. elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling. Unlike Unc93a, another homolog of the C. elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9; the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction. Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indicating that Unc93b plays an important role in innate immunity.
Product Categories/Family for anti-Unc93b antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
66,631 Da
NCBI Official Full Name
UNC93B1 protein, partial
NCBI Official Synonym Full Names
unc-93 homolog B1 (C. elegans)
NCBI Official Symbol
UNC93B1
NCBI Official Synonym Symbols
IIAE1; UNC93; UNC93B; Unc-93B1
NCBI Protein Information
protein unc-93 homolog B1
UniProt Protein Name
Protein unc-93 homolog B1
UniProt Gene Name
UNC93B1
UniProt Synonym Gene Names
UNC93; UNC93B; Unc-93B1; hUNC93B1
UniProt Entry Name
UN93B_HUMAN
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Product Notes
The Unc93b unc93b1 (Catalog #AAA302569) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Unc93b Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Unc93b can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Unc93b unc93b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Unc93b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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