IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using USP19 antibody.)
Rabbit anti-Human, Mouse USP19 Polyclonal Antibody | anti-USP19 antibody
USP19 Antibody
Gene Names
USP19; ZMYND9
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
USP19, Antibody; USP19 Antibody; deubiquitinating enzyme 19; EC 3.1.2.15; KIAA0891; UB19; ubiquitin carboxyl-terminal hydrolase 19; anti-USP19 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total USP19 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1419
Applicable Applications for anti-USP19 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human USP19.
Target Name
USP19
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using USP19 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using USP19 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells, using USP19 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells, using USP19 antibody.)
Related Product Information for anti-USP19 antibody
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.Nagase T., DNA Res. 5:355-364(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Product Categories/Family for anti-USP19 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
150,659 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 19 isoform 1
NCBI Official Synonym Full Names
ubiquitin specific peptidase 19
NCBI Official Symbol
USP19
NCBI Official Synonym Symbols
ZMYND9
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 19
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 19
UniProt Gene Name
USP19
UniProt Synonym Gene Names
KIAA0891; ZMYND9
UniProt Entry Name
UBP19_HUMAN
Similar Products
Product Notes
The USP19 usp19 (Catalog #AAA305710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP19 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's USP19 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the USP19 usp19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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