VEGF peptide
VEGF (A19) Blocking Peptide
Synonyms
VEGF, Peptide; VEGF (A19) Blocking Peptide; VEGF peptide
Host
Rabbit
Clonality
Polyclonal
Specificity
VEGF MBS443051 (A19) reacts with VEGF of human orgin by western blotting. Western blotting starting dilution: 1:200.
Immunoprecipitation: Not yet tested
Immunohistochemistry: Not yet tested
Immunoprecipitation: Not yet tested
Immunohistochemistry: Not yet tested
Form/Format
Each vial contains 200ug/ml of affinity purified rabbit IgG VEGF MBS440051 (A19), in 1ml PBS containing 0.1% sodium azide and 0.2% gelatin,
Sequence Length
317
Origin
VEGF (A19) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to a domain near the amino terminus of Human VEGF.
Competition Studies
A blocking peptide is also availble, MBS443051, for use in competition studies. Each vial contains 100ug of peptide in 0.5ml PBS with 0.1% sodium azide and 100ug BSA.
Preparation and Storage
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
Related Product Information for VEGF peptide
The vascular endothelial growth factor (VEGF) family currently includes VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF (1). VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis (2). Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process (3&4). To date 5 different isoforms of VEGF have been described, VEGF 121, VEGF 145, VEGF 165, VEGF 165b, and VEGF 189(4&5). These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells (5).
Product Categories/Family for VEGF peptide
References
1. Matsumoto T, Claesson-Welsh L. 2001. VEGF receptor signal transduction. Sci STKE 112:RE21.2. Shibuya M. 2001. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct 26(1):25-35.3. Hasan J, Jasyson GC. 2001. VEGF antagonists. Expert Opin Biol Ther 1(4):703-18.4. Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. 2002. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res 62(14):4123-31.5. Neufel G, Cohen T, Gengrinovitch S, Poltorak Z. 1999. Vascular endothelial growth factor (VEGF) and its receptors. FASEB 13(1):9-22.
NCBI and Uniprot Product Information
Similar Products
Product Notes
The VEGF vegfa (Catalog #AAA63037) is a Peptide produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "VEGF, Polyclonal Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.