Rabbit anti-Human, Mouse VKORC1 Polyclonal Antibody | anti-VKORC1 antibody

VKORC1 Antibody

Cat. Num. AAA39895

• Gene Names: VKORC1; VKOR; MST134; MST576; VKCFD2; EDTP308; IMAGE3455200
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: VKORC1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: VKORC1, Antibody; VKORC1 Antibody; VKORC1; VKOR; MST134; MST576; VKCFD2; EDTP308; IMAGE3455200; MSTP134; MSTP576; UNQ308/PRO351; Vitamin K epoxide reductase complex subunit 1; Vitamin K1 2; 3-epoxide reductase subunit 1; vitamin K epoxide reductase complex, subunit 1; anti-VKORC1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: VKORC1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 163

• Applicable Applications for anti-VKORC1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1.
• Buffer: VKORC1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Homology: Predicted Species reactivity based on immunogen sequence: Bovine: (100%), Rat (87%).
• Preparation and Storage: VKORC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of VKORC1 in human lung tissue with VKORC1 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of VKORC1 in A549 cell lysate with VKORC1 antibody at 1 μg/mL.)

Related Product Information for anti-VKORC1 antibody

VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.

NCBI and Uniprot Product Information

• NCBI GI #: 13124770
• NCBI GeneID: 79001
• NCBI Accession #: NP_076869
• NCBI GenBank Nucleotide #: NM_024006.4
• UniProt Accession #: Q9BQB6; Q6UX90; Q7Z2R4; A6NIQ6; B2R4Z6
• NCBI Official Full Name: vitamin K epoxide reductase complex subunit 1 isoform 1
• NCBI Official Synonym Full Names: vitamin K epoxide reductase complex, subunit 1
• NCBI Official Symbol: VKORC1
• NCBI Official Synonym Symbols: VKOR; MST134; MST576; VKCFD2; EDTP308; IMAGE3455200
• NCBI Protein Information: vitamin K epoxide reductase complex subunit 1; phylloquinone epoxide reductase; vitamin K1 2,3-epoxide reductase subunit 1; vitamin K dependent clotting factors deficiency 2; vitamin K1 epoxide reductase (warfarin-sensitive)
• UniProt Protein Name: Vitamin K epoxide reductase complex subunit 1
• UniProt Gene Name: VKORC1
• UniProt Synonym Gene Names: VKOR
• UniProt Entry Name: VKOR1_HUMAN