IF (Immunofluorescence)
(Immunofluorescence of WWC1 in mouse brain tissue with WWC1 antibody at 20 μg/ml.)
Rabbit WWC1 Polyclonal Antibody | anti-WWC1 antibody
WWC1 Antibody
Gene Names
WWC1; KIBRA; HBEBP3; HBEBP36; MEMRYQTL; PPP1R168
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
WWC1 antibody is affinity chromatography purified via peptide column.
Synonyms
WWC1, Antibody; WWC1 Antibody; WW and C2 domain containing 1; HBEBP3; HBEBP36; KIBRA; MEMRYQTL; anti-WWC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist; this antibody will detect all three isoforms.
Purity/Purification
WWC1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1119
Applicable Applications for anti-WWC1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
WWC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human WWC1.
Buffer
WWC1 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
WWC1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of WWC1 in mouse brain tissue with WWC1 antibody at 20 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of WWC1 in mouse brain tissue with WWC1 antibody at 20 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of WWC1 in mouse brain tissue with WWC1 antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of WWC1 in mouse brain tissue with WWC1 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of WWC1 in human brain tissue lysate with WWC1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of WWC1 in human brain tissue lysate with WWC1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-WWC1 antibody
The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 123 kDa
Observed: 110 kDa
Observed: 110 kDa
NCBI Official Full Name
protein KIBRA isoform 1
NCBI Official Synonym Full Names
WW and C2 domain containing 1
NCBI Official Symbol
WWC1
NCBI Official Synonym Symbols
KIBRA; HBEBP3; HBEBP36; MEMRYQTL; PPP1R168
NCBI Protein Information
protein KIBRA; protein WWC1; HBeAg-binding protein 3; kidney and brain protein; WW, C2 and coiled-coil domain containing 1; protein phosphatase 1, regulatory subunit 168
UniProt Protein Name
Protein KIBRA
UniProt Gene Name
WWC1
UniProt Synonym Gene Names
KIAA0869; KIBRA
UniProt Entry Name
KIBRA_HUMAN
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Product Notes
The WWC1 wwc1 (Catalog #AAA40788) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WWC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's WWC1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the WWC1 wwc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WWC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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