Rabbit anti-Human, Mouse XIAP Polyclonal Antibody | anti-XIAP antibody

XIAP Antibody

Cat. Num. AAA39880

• Gene Names: XIAP; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: XIAP Antibody is affinity chromatography purified via peptide column.
• Synonyms: XIAP, Antibody; XIAP Antibody; XIAP; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; IAP3; E3 ubiquitin-protein ligase XIAP; Baculoviral IAP repeat-containing protein 4; ILP; X-linked inhibitor of apoptosis; anti-XIAP antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: XIAP Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 497

• Applicable Applications for anti-XIAP antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: XIAP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP.
• Buffer: XIAP Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of XIAP in mouse kidney tissue with XIAP antibody at 20 μg/mL.Red: XIAP Antibody (3331)Blue: DAPI staining)

IHC (Immunohistochemistry)

(Immunohistochemistry of XIAP in mouse kidney tissue with XIAP antibody at 5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of XIAP in Human Kidney tissue with XIAP antibody at 10 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemical staining of human kidney tissue using XIAP antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of XIAP in human kidney lysate with XIAP antibody at (A) 0.5, (B) 1 , and (C) 2 μg/mL, respectively.)

Related Product Information for anti-XIAP antibody

XIAP Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The X-chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases-3, -7, and -9. Upregulation of XIAP expression can protect cells from apoptosis induced by low level radiation; conversely, decreased XIAP expression by antisense targeting resulted in increased cell death following low level radiation. Two negative regulators, termed XAF-1 and Smac, can bind and inhibit XIAP activity.

NCBI and Uniprot Product Information

• NCBI GI #: 32528299
• NCBI GeneID: 331
• NCBI Accession #: NP_001158
• NCBI GenBank Nucleotide #: NM_001167.3
• UniProt Accession #: P98170; Q9NQ14; D3DTF2
• Molecular Weight: 56,685 Da
• NCBI Official Full Name: E3 ubiquitin-protein ligase XIAP
• NCBI Official Synonym Full Names: X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
• NCBI Official Symbol: XIAP
• NCBI Official Synonym Symbols: API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
• NCBI Protein Information: E3 ubiquitin-protein ligase XIAP; X-linked IAP; IAP-like protein; inhibitor of apoptosis protein 3; baculoviral IAP repeat-containing protein 4
• UniProt Protein Name: E3 ubiquitin-protein ligase XIAP
• UniProt Gene Name: XIAP
• UniProt Synonym Gene Names: API3; BIRC4; IAP3; ILP; hILP; IAP-3; hIAP-3; hIAP3; X-linked IAP
• UniProt Entry Name: XIAP_HUMAN