Rabbit anti-Human ZACN Polyclonal Antibody | anti-ZACN antibody

ZACN Antibody (C-term)

Cat. Num. AAA285909

• Gene Names: ZACN; L2; ZAC; ZAC1; LGICZ; LGICZ1
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: ZACN, Antibody; ZACN Antibody (C-term); Zinc-activated ligand-gated ion channel; Ligand-gated ion channel zinc-activated 1; Ligand-gated ion-channel receptor L2; ZACN; L2; LGICZ; LGICZ1; ZAC; anti-ZACN antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This ZACN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human ZACN.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Positions: 331-360

• Applicable Applications for anti-ZACN antibody: IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Clone Names: RB26010
• Function: Zinc-activated ligand-gated ion channel.
• Cellular Location: Cell membrane; Multi-pass membrane protein
• Tissue Location: Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(ZACN Antibody (C-term) (AAA285909) IHC analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZACN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(Western blot analysis of ZACN Antibody (C-term) (AAA285909) in A375 cell line lysates (35ug/lane). ZACN (arrow) was detected using the purified Pab.)

Related Product Information for anti-ZACN antibody

ZACN is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels.

References

Houtani, T., et al. Biochem. Biophys. Res. Commun. 335(2):277-285(2005)
Davies, P.A., et al. J. Biol. Chem. 278(2):712-717(2003)

NCBI and Uniprot Product Information

• NCBI GI #: 206725456
• NCBI GeneID: 353174
• NCBI Accession #: NP_851321.2
• NCBI GenBank Nucleotide #: NM_180990.3
• UniProt Accession #: Q401N2; Q2TB29; Q6ZWK3; Q86YW4
• Molecular Weight: 45816
• NCBI Official Full Name: zinc-activated ligand-gated ion channel
• NCBI Official Synonym Full Names: zinc activated ligand-gated ion channel
• NCBI Official Symbol: ZACN
• NCBI Official Synonym Symbols: L2; ZAC; ZAC1; LGICZ; LGICZ1
• NCBI Protein Information: zinc-activated ligand-gated ion channel
• UniProt Protein Name: Zinc-activated ligand-gated ion channel
• UniProt Gene Name: ZACN
• UniProt Synonym Gene Names: L2; LGICZ; LGICZ1; ZAC
• UniProt Entry Name: ZACN_HUMAN