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product-image-AAA81582_SDS_PAGE15.jpg SDS-PAGE

IgM Native Protein

Human IgM

Applications
Western Blot, ELISA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
IgM; N/A; Human IgM; IgM native protein
Ordering
Host
Purified from pooled normal human serum
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid
Applicable Applications for IgM native protein
WB (Western Blot), ELISA
Peptide
Full length native human IgM
Storage Buffer
50mM Tris,200mM Nacl,PH8.0
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles

SDS-PAGE

product-image-AAA81582_SDS_PAGE15.jpg SDS-PAGE
Related Product Information for IgM native protein
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ’natural’ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences. Class specific anti immunoglobulin antibodies are useful for: The characterization of malignant B cell proliferations. All but acute lymphocytic leukemias share either surface or intra cytoplasmic Ig with an isotypic restriction, which suggest the monoclonal nature of the cell population. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt’s lymphoma bear surface IgM, whereas plasmocytes from Waldenstr .

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
IgM, partial

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Product Notes

The IgM (Catalog #AAA81582) is a Native Protein produced from Purified from pooled normal human serum and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IgM can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IgM for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgM, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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