WB (Western Blot)
(The whole cell lysate derived from A431 was immunoblotted by Rabbit anti STAT3 antibody at 1:500. An immunoreactive band was observed around 94kDa.)
Rabbit STAT3 Antibody | anti-STAT3 antibody
Rabbit anti STAT3
Gene Names
STAT3; APRF; HIES; FLJ20882; MGC16063
Reactivity
Human, Rat, Mouse, Dog, Bovine
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA
Purity
The Rabbit IgG is purified by Epitope -Affinity Purification.
Synonyms
STAT3; N/A; Rabbit anti STAT3; Rabbit anti-Phospho-STAT3; Signal transducer and activator of transcription 3 (STAT3); anti-STAT3 antibody
Host
Rabbit
Reactivity
Human, Rat, Mouse, Dog, Bovine
Specificity
This antibody recognizes STAT3 protein.
Purity/Purification
The Rabbit IgG is purified by Epitope -Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
Applicable Applications for anti-STAT3 antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
Antigen Preparation
A synthetic peptide from C-terminus of human STAT3 protein. This sequence is identical to human, mouse, rat, chicken, dog, and bovine origins.
Positive Control
A431 whole cell lysate
Cellular Location
Nuclear
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
WB (Western Blot)
(The whole cell lysate derived from A431 was immunoblotted by Rabbit anti STAT3 antibody at 1:500. An immunoreactive band was observed around 94kDa.)
WB (Western Blot)
(The whole cell lysate derived from A431 was immunoblotted by Rabbit anti STAT3 antibody at 1:500. An immunoreactive band was observed around 94kDa.)
Related Product Information for anti-STAT3 antibody
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT3 induces STAT dimerization, nuclear translocation and DNA binding. Stat3 is constitutively activated in a number of human tumors. Stat3- activated transcription seems to be regulated by serine phosphorylation at Tyr 705 and Ser727.
References
Ritsuko Matsuo et al. A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody. Journal of Immunological Methods. Volume 247, Issues 1-2, 1 January 2001, Pages 141-151
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94 kDa
NCBI Official Full Name
signal transducer and activator of transcription 3 isoform 1
NCBI Official Synonym Full Names
signal transducer and activator of transcription 3 (acute-phase response factor)
NCBI Official Symbol
STAT3
NCBI Official Synonym Symbols
APRF; HIES; FLJ20882; MGC16063
NCBI Protein Information
signal transducer and activator of transcription 3; OTTHUMP00000198123; OTTHUMP00000198128; DNA-binding protein APRF; acute-phase response factor
UniProt Protein Name
Signal transducer and activator of transcription 3
UniProt Gene Name
STAT3
UniProt Synonym Gene Names
APRF
UniProt Entry Name
STAT3_HUMAN
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Product Notes
The STAT3 stat3 (Catalog #AAA71404) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti STAT3 reacts with Human, Rat, Mouse, Dog, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's STAT3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the STAT3 stat3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAT3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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