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product-image-AAA329564_WB13.jpg WB (Western Blot) (Western blot analysis of RUNX2 in lysates of  Mouse thymus  , using RUNX2 Antibody(AF4770).)

Rabbit RUNX2 Antibody | anti-RUNX2 antibody

RUNX2 Antibody

Gene Names
RUNX2; CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Peptide affinity purification
Synonyms
RUNX2; N/A; RUNX2 Antibody; anti-RUNX2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Specificity
RUNX2 Antibody detects endogenous levels of total RUNX2.
Purity/Purification
Peptide affinity purification
Form/Format
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-RUNX2 antibody
ELISA, WB (Western Blot)
Immunogen
A synthesized peptide derived from human RUNX2, corresponding to a region within the internal amino acids.
Preparation and Storage
Store at -20°C.

WB (Western Blot)

(Western blot analysis of RUNX2 in lysates of  Mouse thymus  , using RUNX2 Antibody(AF4770).)

product-image-AAA329564_WB13.jpg WB (Western Blot) (Western blot analysis of RUNX2 in lysates of  Mouse thymus  , using RUNX2 Antibody(AF4770).)

WB (Western Blot)

(Western blot analysis of extracts from NIH-3T3 cells, using RUNX2 Antibody. The lane on the left was treated with blocking peptide.)

product-image-AAA329564_WB15.jpg WB (Western Blot) (Western blot analysis of extracts from NIH-3T3 cells, using RUNX2 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-RUNX2 antibody
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
860
UniProt Accession #
NCBI Official Full Name
Runt-related transcription factor 2
NCBI Official Synonym Full Names
runt-related transcription factor 2
NCBI Official Symbol
RUNX2
NCBI Official Synonym Symbols
CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1
NCBI Protein Information
runt-related transcription factor 2; PEA2-alpha A; PEBP2-alpha A; oncogene AML-3; acute myeloid leukemia 3 protein; SL3-3 enhancer factor 1 alpha A subunit; osteoblast-specific transcription factor 2; SL3/AKV core-binding factor alpha A subunit; core-bind
UniProt Protein Name
Runt-related transcription factor 2
UniProt Gene Name
RUNX2
UniProt Synonym Gene Names
AML3; CBFA1; OSF2; PEBP2A; CBF-alpha-1; OSF-2; PEA2-alpha A; PEBP2-alpha A
UniProt Entry Name
RUNX2_HUMAN

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Product Notes

The RUNX2 runx2 (Catalog #AAA329564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RUNX2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RUNX2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the RUNX2 runx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RUNX2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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