RNA-binding motif protein, Y chromosome, family 1 member A1 Recombinant Protein | RBMY1A1 recombinant protein

Recombinant Human RNA-binding motif protein, Y chromosome, family 1 member A1

Cat. Num. AAA114534

• Gene Names: RBMY1A1; RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: RNA-binding motif protein, Y chromosome, family 1 member A1; N/A; Recombinant Human RNA-binding motif protein, Y chromosome, family 1 member A1; RNA-binding motif protein 1; RNA-binding motif protein 2; Y chromosome RNA recognition motif 1; hRBMY; RBMY1A1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-459aa; Partial
• Sequence: MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPADAKNAAKDMNGKSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSRGGTRGWLPSHEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDYAYRDYGHSSWDEHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTSHGAPPARGPRMSYGGSTCHAYSNTRDRYGRSWESYSSCGDFHYCDREHVCRKDQRNPPS
• Sequence Length: 496

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for RBMY1A1 recombinant protein

RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.

Product Categories/Family for RBMY1A1 recombinant protein

Epigenetics and Nuclear Signaling

References

A Y chromosome gene family with RNA-binding protein homology candidates for the azoospermia factor AZF controlling human spermatogenesis.Ma K., Inglis J.D., Sharkey A., Bickmore W.A., Hill R.E., Prosser E.J., Speedson R.M., Thomson E.J., Jobling M.Cell 75:1287-1295(1993) The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A., Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C.Nature 423:825-837(2003) Structure and organization of the RBMY genes on the human Y chromosome transposition and amplification of an ancestral autosomal hnRNPG gene.Chai N.-N., Zhou H., Hernandez J., Najmabadi H., Bhasin S., Yen P.H.Genomics 49:283-289(1998) Expression of RBM in the nuclei of human germ cells is dependent on a critical region of the Y chromosome long arm.Elliott D.J., Millar M.R., Oghene K., Ross A., Kiesewetter F., Pryor J., McIntyre M., Hargreave T.B., Saunders P.T.K., Vogt P.H., Chandley A.C., Cooke H.Proc. Natl. Acad. Sci. U.S.A. 94:3848-3853(1997) T-STAR/ETOILE a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.Venables J.P., Vernet C., Chew S.L., Elliott D.J., Cowmeadow R.B., Wu J., Cooke H.J., Artzt K., Eperon I.C.Hum. Mol. Genet. 8:959-969(1999) RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.Venables J.P., Elliott D.J., Makarova O.V., Makarov E.M., Cooke H.J., Eperon E.C.Hum. Mol. Genet. 9:685-694(2000) hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.Hofmann Y., Wirth B.Hum. Mol. Genet. 11:2037-2049(2002) The role of potential splicing factors including RBMY, RBMX, hnRNPG-T and STAR proteins in spermatogenesis.Elliott D.J.Int. J. Androl. 27:328-334(2004) The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction.Skrisovska L., Bourgeois C.F., Stefl R., Grellscheid S.-N., Kister L., Wenter P., Elliott D.J., Stevenin J., Allain F.H.-T.EMBO Rep. 8:372-379(2007)

NCBI and Uniprot Product Information

• NCBI GI #: 4826974
• NCBI GeneID: 5940
• NCBI Accession #: NP_005049.1
• NCBI GenBank Nucleotide #: NM_005058.2
• UniProt Accession #: P0DJD3; Q15376; Q15377; Q15414; Q6NSB5; Q86VU6; Q8NHR0
• Molecular Weight: 55.9 kDa
• NCBI Official Full Name: RNA-binding motif protein, Y chromosome, family 1 member A1
• NCBI Official Synonym Full Names: RNA binding motif protein, Y-linked, family 1, member A1
• NCBI Official Symbol: RBMY1A1
• NCBI Official Synonym Symbols: RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C
• NCBI Protein Information: RNA-binding motif protein, Y chromosome, family 1 member A1
• UniProt Protein Name: RNA-binding motif protein, Y chromosome, family 1 member A1
• UniProt Gene Name: RBMY1A1
• UniProt Synonym Gene Names: RBM1; RBM2; YRRM1; YRRM2; hRBMY
• UniProt Entry Name: RBY1A_HUMAN