SDS-PAGE
PSGL-1 / CD162 / SELPLG recombinant protein
Recombinant Mouse PSGL-1 / CD162 / SELPLG Protein (Fc tag)
Gene Names
Selplg; CD162; Psgl1; Selp1; Selpl; Psgl-1
Purity
> 85 % as determined by SDS-PAGE
Synonyms
PSGL-1 / CD162 / SELPLG; N/A; Recombinant Mouse PSGL-1 / CD162 / SELPLG Protein (Fc tag); CD162, Psgl-1, Psgl1, Selp1, Selpl; PSGL-1 / CD162 / SELPLG recombinant protein
Host
Human Cells.
Purity/Purification
> 85 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% Tween 80
Sequence Length
397
Source
Mouse
Predicted N Terminal
Leu 18
Protein Construction
A DNA sequence encoding the extracellular domain of mouse SELPLG (Q62170) (Met 1-Cys 307) was fused with the Fc region of human IgG1 at the C-terminus.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Molecular Mass
The secreted recombinant mouse SELPLG /Fc is a disulfide-linked homodimer. The reduced monomer comprises 531 amino acids and has a calculated molecular mass of 57.4 kDa. As a result of glycosylation, the apparent molecular mass of rmSELPLG/Fc monmer is approximately 82..
Reconstitution
It is recommended that sterile water(200uL) be addded to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV- Vis.
Concentration is measured by UV- Vis.
Stability
Samples are stable for up to twelve months from date of receipt at -70°C
Preparation and Storage
Store it under sterile conditions at -20°C to -80°C . It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for PSGL-1 / CD162 / SELPLG recombinant protein
P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~120 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Description: A DNA sequence encoding the extracellular domain of mouse SELPLG (Q62170) (Met 1-Cys 307) was fused with the Fc region of human IgG1 at the C-terminus.
Description: A DNA sequence encoding the extracellular domain of mouse SELPLG (Q62170) (Met 1-Cys 307) was fused with the Fc region of human IgG1 at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
P-selectin glycoprotein ligand 1
NCBI Official Synonym Full Names
selectin, platelet (p-selectin) ligand
NCBI Official Symbol
Selplg
NCBI Official Synonym Symbols
CD162; Psgl1; Selp1; Selpl; Psgl-1
NCBI Protein Information
P-selectin glycoprotein ligand 1
UniProt Protein Name
P-selectin glycoprotein ligand 1
UniProt Gene Name
Selplg
UniProt Synonym Gene Names
Selp1; Selpl; PSGL-1
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Product Notes
The PSGL-1 / CD162 / SELPLG selplg (Catalog #AAA173586) is a Recombinant Protein produced from Human Cells. and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PSGL-1 / CD162 / SELPLG, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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