Human HAI-2 ELISA Kit | SPINT2 elisa kit
Human HAI-2 ELISA Kit
Gene Names
SPINT2; PB; Kop; HAI2; DIAR3; HAI-2
Reactivity
Human
Synonyms
HAI-2; N/A; Human HAI-2 ELISA Kit; HAI2; KOP; Kunitz-type protease inhibitor 2; Hepatocyte growth factor activator inhibitor type 2; Placental bikunin; SPINT2 elisa kit
Reactivity
Human
Specificity
The Human HAI-2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human HAI-2 proteins within the range of 31.2 pg/ml - 2000 pg/ml.
Sequence Length
195
Samples
Cell Culture Supernates, Serum, Plasma, Cell Lysates, Tissue Homogenates
Sensitivity
<10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Related Product Information for SPINT2 elisa kit
Principle of the Assay: The Human HAI-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human HAI-2 in Cell Culture Supernates, Serum, Plasma, Cell Lysates, Tissue Homogenates. This assay employs an antibody specific for Human HAI-2 coated on a 96-well plate. Standards and samples are pipetted into the wells and HAI-2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human HAI-2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of HAI-2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
Background: Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,828 Da
NCBI Official Full Name
kunitz-type protease inhibitor 2 isoform b
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kunitz type 2
NCBI Official Symbol
SPINT2
NCBI Official Synonym Symbols
PB; Kop; HAI2; DIAR3; HAI-2
NCBI Protein Information
kunitz-type protease inhibitor 2
UniProt Protein Name
Kunitz-type protease inhibitor 2
UniProt Gene Name
SPINT2
UniProt Synonym Gene Names
HAI2; KOP; HAI-2
UniProt Entry Name
SPIT2_HUMAN
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Product Notes
The Human SPINT2 spint2 (Catalog #AAA263088) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263088 ELISA Kit recognizes Human SPINT2. It is sometimes possible for the material contained within the vial of "HAI-2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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